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2-(PIPERIDIN-1-YLSULFONYL)ANILINE, also known as TAK-475, is a sulfonamide derivative with the molecular formula C13H18N2O2S. It is a chemical compound that exhibits potential antihyperlipidemic and antihypercholesterolemic activities. TAK-475 functions by inhibiting squalene epoxidase, a key enzyme in cholesterol biosynthesis. By blocking this enzyme, it effectively lowers levels of low-density lipoprotein (LDL) cholesterol in the blood, thereby reducing the risk of cardiovascular diseases. TAK-475 is currently under investigation for its potential use in treating hypercholesterolemia, a condition characterized by elevated blood cholesterol levels that can lead to heart disease and stroke.

436095-30-6

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436095-30-6 Usage

Uses

Used in Pharmaceutical Industry:
2-(PIPERIDIN-1-YLSULFONYL)ANILINE is used as a therapeutic agent for the treatment of hypercholesterolemia. It is employed for its ability to lower LDL cholesterol levels in the blood, which can help reduce the risk of heart disease and stroke in patients with high cholesterol levels.
Used in Cardiovascular Health Applications:
2-(PIPERIDIN-1-YLSULFONYL)ANILINE is used as a cholesterol-lowering agent to manage and prevent cardiovascular diseases. Its mechanism of action involves inhibiting squalene epoxidase, which in turn reduces the production of cholesterol and lowers LDL cholesterol levels, contributing to improved cardiovascular health.
Used in Research and Development:
2-(PIPERIDIN-1-YLSFONYL)ANILINE is used as a chemical compound in research for its potential applications in the development of new drugs and therapies targeting cholesterol-related conditions. Its unique properties and mechanism of action make it a valuable candidate for further investigation and potential use in the treatment of hypercholesterolemia and related cardiovascular diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 436095-30-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,3,6,0,9 and 5 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 436095-30:
(8*4)+(7*3)+(6*6)+(5*0)+(4*9)+(3*5)+(2*3)+(1*0)=146
146 % 10 = 6
So 436095-30-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H16N2O2S/c12-10-6-2-3-7-11(10)16(14,15)13-8-4-1-5-9-13/h2-3,6-7H,1,4-5,8-9,12H2

436095-30-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-piperidin-1-ylsulfonylaniline

1.2 Other means of identification

Product number -
Other names 2-(piperidin-1-ylsulfonyl)aniline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:436095-30-6 SDS

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