437708-86-6

Basic information

• Product Name: 2,4-DIBROMO-6-NITROQUINOLINE
• Synonyms: 2,4-DIBROMO-6-NITROQUINOLINE
• CAS NO: 437708-86-6
• Molecular Formula: C₉H₄Br₂N₂O₂
• Molecular Weight: 331.94826
• Mol File: 437708-86-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,4-DIBROMO-6-NITROQUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DIBROMO-6-NITROQUINOLINE(437708-86-6)
• EPA Substance Registry System: 2,4-DIBROMO-6-NITROQUINOLINE(437708-86-6)

Safety Data

• Hazardous Substances Data: 437708-86-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2,4-DIBROMO-6-NITROQUINOLINE is used as a chemical intermediate for the synthesis of pharmaceuticals. Its unique structure allows it to be a building block in the development of new drugs, potentially contributing to the creation of novel therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, 2,4-DIBROMO-6-NITROQUINOLINE is utilized as an intermediate in the production of agrochemicals. Its chemical properties make it suitable for the synthesis of compounds that can be used in pest control and crop protection.
Used in Photographic Chemical Industry:
2,4-DIBROMO-6-NITROQUINOLINE is employed in the manufacturing of photographic chemicals. Its chemical reactivity and solubility profile are advantageous in the development of photographic film and paper processing chemicals.
Used in Dye and Pigment Production:
2,4-DIBROMO-6-NITROQUINOLINE is used as a precursor in the production of dyes and pigments. Its chemical structure contributes to the color properties of these products, making it valuable in the colorant industry for creating a range of hues.
Used in Disease Treatment Research:
2,4-DIBROMO-6-NITROQUINOLINE has been studied for its potential use in the treatment of various diseases, including cancer and infectious diseases. Its chemical properties are of interest to researchers exploring new therapeutic approaches, although it is considered a potential mutagen and requires careful handling in laboratory settings.

Upstream product

• 863723-28-8 6-nitro-1H-quinoline-2,4-dione 
• 20151-40-0 2,4-dibromoquinoline 
• 70254-44-3 2,4-dihydroxyquinoline 
• 264260-06-2 6-nitro-quinoline-2,4-diol 
• 100-01-6 4-nitro-aniline 
• 5502-62-5 N-(4-nitro-phenyl)-malonamic acid 
• 10390-08-6 ethyl 3-((4-nitrophenyl)amino)-3-oxopropanoate 
• 264260-06-2 4-hydroxy-6-nitroquinolin-2(1H)-one 

Downstream Products

• 143954-73-8 4-Bromo-6-nitro-2-piperazin-1-yl-quinoline 

Relevant articles and documents

Looking for new antileishmanial derivatives in 8-nitroquinolin-2(1H)-one series

From a recently identified antileishmanial pharmacophore, a structure-activity relationship study was conducted by introducing various aminated, phenoxy or thiophenoxy moieties at position 4 of the 8-nitroquinolin-2(1H)-one scaffold, using SNAr

The discovery of quinoline derivatives, as NF-κB inducing kinase (NIK) inhibitors with anti-inflammatory effects in vitro, low toxicities against T cell growth

NIK is a critical regulatory protein of the non-classical NF-kB pathway, and its dysregulated activation has been proved to be one of the pathogenic factors in a variety of autoimmune diseases and inflammatory diseases. Nevertheless, its corresponding dev

Syntheses and binding affinities of 6-nitroquipazine analogues for serotonin transporter. Part 4: 3-Alkyl-4-halo-6-nitroquipazines

On the basis of the structure-activity relationship (SAR) of 4-chloro-6-nitroquipazine (Ki = 0.03 nM) and 3-fluoropropyl-6- nitroquipazine (Ki = 0.32 nM), 3-alkyl-4-halo-6-nitroquipazines were synthesized and tested for their potenti

Syntheses and binding affinities of 6-nitroquipazine analogues for serotonin transporter. Part 2: 4-Substituted 6-nitroquipazines

Eleven 4-substituted derivatives of 6-nitroquipazine were synthesized and evaluated for their abilities to displace [3H]citalopram binding to the rat cortical synaptic membranes. Among them, 4-chloro-6-nitroquipazine was shown to possess the hi