440323-64-8Relevant articles and documents
Copper-catalyzed coupling reaction of 2-thioxo-4-quinazolinone and thieno[3,2-d]pyrimidin-4-one methane sulphonamide with aryl iodides: Preparation of potential COX-2 selective inhibitors
Perdicaro, Antonio,Granata, Giuseppe,Marrazzo, Agostino,Santagati, Andrea
, p. 723 - 737 (2008/09/16)
Thio-aryl methane sulfonamide derivatives of 4-quinazolinone and thieno[2,3-d]pyrimidin-4-one were synthesized using powdery copper/copper(I) iodide as catalyst; their structural elucidation is also reported. These derivatives were planned as sulfur bioisosteres of selective COX-2 inhibitor drugs. Copyright Taylor & Francis Group, LLC.