441016-97-3

Basic information

• Product Name: 2(1H)-Pentalenone,hexahydro-5-methoxy-,(3a-alpha-,5-bta-,6a-alpha-)-(9CI)
• Synonyms: 2(1H)-Pentalenone,hexahydro-5-methoxy-,(3a-alpha-,5-bta-,6a-alpha-)-(9CI)
• CAS NO: 441016-97-3
• Molecular Formula: C9H14O2
• Molecular Weight: 154.21
• Product Categories: CYCLOPENTANE
• Mol File: 441016-97-3.mol

Chemical Properties

• Boiling Point: 233.1±23.0 °C(Predicted)
• Appearance: /
• Density: 1.06±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 2(1H)-Pentalenone,hexahydro-5-methoxy-,(3a-alpha-,5-bta-,6a-alpha-)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-Pentalenone,hexahydro-5-methoxy-,(3a-alpha-,5-bta-,6a-alpha-)-(9CI)(441016-97-3)
• EPA Substance Registry System: 2(1H)-Pentalenone,hexahydro-5-methoxy-,(3a-alpha-,5-bta-,6a-alpha-)-(9CI)(441016-97-3)

Safety Data

• Hazardous Substances Data: 441016-97-3(Hazardous Substances Data)

Usage

Molecular weight

180.24 g/mol

Occurrence

Naturally occurring compound found in certain plants and fungi

Biological activity

Known for its potential pharmacological properties

Chemical classification

Pentalenolactone derivative

Structure

Contains a six-membered ring with a methoxy group attached

Industrial applications

Important intermediate in the synthesis of various natural products, potential applications in the pharmaceutical industry

Research interest

Unique structure and properties make it a subject of interest for further research and development in the field of medicinal chemistry.

Upstream product

• 481037-34-7 (3'aα,5'β,6'aα)-hexahydro-5'-methoxy-5,5-dimethylspiro[1,3-dioxane-2,2'(1'H)-pentalene] 
• 952023-05-1 (3aR,5s,6aS)-3-methoxy-7,7-(ethylidene acetal)bicyclo[3.3.0]octane 
• 71909-64-3 (3aR,5s,6aS)-5-hydroxyhexahydropentalen-2(1H)-one 
• 74-88-4 methyl iodide 
• 481047-54-5 (3'aα,5'α,6'aα)-hexahydro-5'-methoxy-5,5-dimethylspiro[1,3-dioxane-2,2'(1'H)-pentalene] 

Downstream Products

• 600700-65-0 (4aα,6β,7aα)-hexahydro-6-methoxycyclopenta[c]pyran-3(1H)-one 
• 600700-65-0 4aS-(4aα,6α,7aα)-hexahydro-6-methoxy-cycopenta[c]pyran-3(1H)-one 
• 600700-65-0 (4aα,6α,7aα)-hexahydro-6-methoxycyclopenta[c]pyran-3(1H)-one 

Relevant articles and documents

HEXAHYDROPENTALENO DERIVATIVES, PREPARATION METHOD AND USE IN MEDICINE THEREOF

The invention relates to hexahydropentaleno derivatives, the preparation method and use in medicine thereof, and in particular to hexahydropentaleno derivatives or stereo-isomers or pharmaceutically acceptable salts thereof as shown in general formula (I), and to the preparation method therefor and pharmaceutical compositions comprising the derivatives, and to the use thereof as a therapeutical agent, especially as a DPP-IV inhibitor. The definition of each substituent in formula (I) is the same as the definition in the description.

Synthesis and biological evaluation of bicyclo[3.3.0] octane derivatives as dipeptidyl peptidase 4 inhibitors for the treatment of type 2 diabetes

A series of novel bicyclo[3.3.0]octane derivatives have been synthesized and found to be dipeptidyl peptidase 4 (DPP-4) inhibitors. Compounds 10a and 10b demonstrate good efficacies in oral glucose tolerance tests.

Dicyclooctane Derivatives, Preparation Processes and Medical Uses Thereof

The present invention relates to new dicyclooctane derivates represented by general formula (I), preparation processes and pharmaceutical compositions containing them, and to uses for treatment especially for dipeptidyl peptidase inhibitor (DPPIV), in which each substituent group of general formula (I) is as defined in specification.

DICYCLOOCTANE DERIVATES, PREPARATION PROCESSES AND MEDICAL USES THEREOF

The present invention relates to new dicyclooctane derivates represented by general formula (I), preparation processes and pharmaceutical compositions containing them, and to uses for treatment especially for dipeptidyl peptidase inhibitor (DPPIV), in which each substituent group of general formula (I) is as defined in specification

An enantiodivergent trend in microbial Baeyer-Villiger oxidations of functionalized pentalenones by recombinant whole cells expressing monooxygenases from Acinetobacter and Pseudomonas

We have investigated the microbial Baeyer-Villiger oxidations of pentalenones by recombinant whole cells expressing cyclohexanone monooxygenase from Acinetobacter and cyclopentanone monooxygenase from Pseudomonas. The two enzymes display a distinguishable

Whole-cell mediated Baeyer-Villiger oxidation of functionalized bicyclo[3.3.0]ketones by recombinant E. coli

Recombinant whole cells of Escherichia coli overexpressing Acinetobacter sp. NCIMB 9871 cyclohexanone monooxygenase (E.C. 1.14.13.22) have been utilized for the Baeyer-Villiger oxidation of functionalized bicyclo[3.3.0]ketones. Prochiral substrates were d