Cyclization reactions of N-acryloyl-2-aminobenzaldehyde derivatives: formal total synthesis of martinellic acid
N-Alkyl acryloylamides derived from o-aminobenzaldehyde derivatives react with N-alkyl glycine derivatives to provide cis-fused pyrrole[3,2-c]quinolones in moderate yield and high diastereoselectivity. These same substrates engage in a tandem Michael-Mann
He, Yong,Mahmud, Hossen,Moningka, Remond,Lovely, Carl J.,Dias, H.V. Rasika
p. 8755 - 8769
(2007/10/03)
An intramolecular cycloaddition approach to pyrrolo[3,2-c]quinolones
An approach to pyrrolo[3,2-c]quinolones is described which relies on an intramolecular azomethine ylide alkene cycloaddition reaction. Critical to the success of this reaction was the requirement for alkylation of the aniline nitrogen, in the absence of t
He, Yong,Mahmud, Hossen,Wayland, Brian R,Dias, H.V.Rasika,Lovely, Carl J
p. 1171 - 1174
(2007/10/03)
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