443637-62-5

Basic information

• Product Name: 4-(3-bromo-4-methylbenzoyl)morpholine
• Synonyms: 4-(3-bromo-4-methylbenzoyl)morpholine;(3-bromo-4-methylphenyl)(morpholin-4-yl)methanone
• CAS NO: 443637-62-5
• Molecular Formula: C₁₂H₁₄BrNO₂
• Molecular Weight: 284.14906
• Mol File: 443637-62-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(3-bromo-4-methylbenzoyl)morpholine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-bromo-4-methylbenzoyl)morpholine(443637-62-5)
• EPA Substance Registry System: 4-(3-bromo-4-methylbenzoyl)morpholine(443637-62-5)

Safety Data

• Hazardous Substances Data: 443637-62-5(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 7697-26-9 3-bromo-4-methylbenzoic acid 

Downstream Products

• 1007208-11-8 [3-(4-{2-[bis-(4-methoxy-benzyl)-amino]-pyrimidin-5-yl}-2-morpholin-4-yl-5,6-dihydro-pyrrolo[2,3-d]pyrimidin-7-yl)-4-methyl-phenyl]-morpholin-4-yl-methanone 

Relevant articles and documents

PYRROLOPYRIMIDIN DERIVATIVE FOR USE AS PI3K INHIBITOR, AND USE THEREOF

A preventive or therapeutic agent of a proliferative disease such as cancer, having superior PI3K inhibitory effects, superior cell proliferation inhibitory action as well as superior stability in a body and water solubility, is provided. A compound represented by formula (I): [wherein, Q represents a linking group represented by -X-Y-; X represents a single bond -CO-, -CONH-, -CON(C1-4 alkyl)-, -CS-, -CSNH-, -CSN(C1-4 alkyl)-, or -SO2-; Y represents a single bond, arylene or heteroarylene; provided that X and Y are not simultaneously single bonds; and R1 represents -C0-6 alkylene-(A)m-C1-6 alkyl, or C0-6 alkylene-(A)m-C0-6 alkylene-(heterocycle)] or a pharmaceutically acceptable salt thereof.