443734-88-1

Basic information

• Product Name: N-(4-chlorophenyl)-2-naphthamide
• Synonyms: N-(4-chlorophenyl)-2-naphthamide;N-(4-chlorophenyl)naphthalene-2-carboxamide
• CAS NO: 443734-88-1
• Molecular Formula: C₁₇H₁₂ClNO
• Molecular Weight: 281.73628
• Mol File: 443734-88-1.mol

Chemical Properties

• Boiling Point: 373.4±25.0 °C(Predicted)
• Appearance: /
• Density: 1.314±0.06 g/cm3(Predicted)
• PKA: 12.52±0.70(Predicted)
• CAS DataBase Reference: N-(4-chlorophenyl)-2-naphthamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-chlorophenyl)-2-naphthamide(443734-88-1)
• EPA Substance Registry System: N-(4-chlorophenyl)-2-naphthamide(443734-88-1)

Safety Data

• Hazardous Substances Data: 443734-88-1(Hazardous Substances Data)

Upstream product

• 106-47-8 4-chloro-aniline 
• 2243-83-6 2-naphthaloyl chloride 
• 93-09-4 naphthalene-2-carboxylate 

Relevant articles and documents

Quantitative investigation of C-H?π and other intermolecular interactions in a series of crystalline: N -(substituted phenyl)-2-naphthamide derivatives

In this study, we have investigated the nature and characteristics of different intermolecular interactions present in a series of seven N-(substituted phenyl)-2-naphthamides. The seven structures comprise 2-naphthyl ring systems linked by amide bridges to N-bound phenyl 1, or substituted benzene rings 3-7, or in the case of 2, a cyclohexane ring. A common feature of the crystal packing for all but the o-nitro derivative 7 is the presence of a strong intermolecular N-H?O interaction. In the case of 7, the possibility of such an interaction is obviated by the formation of an intramolecular N-H?O hydrogen bond. An additional feature of the crystal packing for 1-6 is the significant roles that C-H?π contacts play in generating three-dimensional networks. In contrast for 7, the intramolecular N-H?O hydrogen bond precludes the formation of molecular chains but the planar nature of this molecule allows significant π?π stacking interactions to stabilize the packing.

One-pot mechanosynthesis of aromatic amides and dipeptides from carboxylic acids and amines

Environmentally friendly one-pot synthesis of amides, bis-amides and dipeptides by mechanochemical carbodiimide-mediated coupling of carboxylic acids and amines is described; high reaction yields and simple aqueous work-up allow for the clean, practical and fast preparation of a variety of compounds containing the amide bond from readily accessible reagents.

Investigating the spectrum of biological activity of substituted quinoline-2-carboxamides and their isosteres

In this study, a series of thirty-five substituted quinoline-2-carboxamides and thirty-three substituted naphthalene-2-carboxamides were prepared and characterized. They were tested for their activity related to the inhibition of photosynthetic electron t