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443956-46-5

(2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-7-yl)-methanol, also known as DHPM, is a heterocyclic organic compound with a dioxinopyridine skeleton. It has potential pharmaceutical applications and has been studied for its ability to act as a kinase inhibitor, targeting various kinases involved in disease processes such as cancer. Additionally, DHPM has demonstrated neuroprotective effects on neuronal cells, indicating its potential as a therapeutic agent for a range of diseases and conditions. Ongoing research is exploring its biological activities and pharmacological properties.

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  • 443956-46-5 Structure

  • Basic information

    1. Product Name: (2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-7-yl)-methanol
    2. Synonyms: (2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-7-yl)-methanol
    3. CAS NO:443956-46-5
    4. Molecular Formula: C8H9NO3
    5. Molecular Weight: 167
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 443956-46-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: (2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-7-yl)-methanol(CAS DataBase Reference)
    10. NIST Chemistry Reference: (2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-7-yl)-methanol(443956-46-5)
    11. EPA Substance Registry System: (2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-7-yl)-methanol(443956-46-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 443956-46-5(Hazardous Substances Data)

443956-46-5 Usage

Uses

Used in Pharmaceutical Industry:
DHPM is used as a kinase inhibitor for its potential to target various kinases involved in disease processes, particularly cancer. Its ability to inhibit these kinases may contribute to the development of therapeutic agents for cancer treatment.
Used in Neuroprotection:
DHPM is used as a neuroprotective agent due to its demonstrated protective effects on neuronal cells. This property suggests its potential use in the development of treatments for neurodegenerative diseases and conditions where neuronal protection is crucial.
Further research into DHPM's biological activities and pharmacological properties is necessary to fully understand its potential applications and optimize its use in various therapeutic areas.

Check Digit Verification of cas no

The CAS Registry Mumber 443956-46-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,3,9,5 and 6 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 443956-46:
(8*4)+(7*4)+(6*3)+(5*9)+(4*5)+(3*6)+(2*4)+(1*6)=175
175 % 10 = 5
So 443956-46-5 is a valid CAS Registry Number.

443956-46-5 Well-known Company Product Price

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  • Aldrich

  • (ADE000037)  (2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-7-yl)methanol  AldrichCPR

  • 443956-46-5

  • ADE000037-1G

  • 9,342.45CNY

  • Detail

443956-46-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-7-yl)-methanol

1.2 Other means of identification

Product number -
Other names (2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-7-yl)methanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:443956-46-5 SDS

443956-46-5Downstream Products

443956-46-5Relevant articles and documents

NITROGEN-CONTAINING BICYCLIC HETEROCYCLES FOR USE AS ANTIBACTERIALS

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Page/Page column 62-63, (2010/02/07)

Cyclohexane and cyclohexene derivatives and pharmaceutically acceptable derivatives hereof useful in methods of treatment of bacterial infections in mammals, particularly man.

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