Electrochemical esterification reaction of alkynes with diols: Via cleavage of carbon-carbon triple bonds without catalyst and oxidant
A novel electrochemical esterification of alkynes for the synthesis of esters was developed in which diols and their derivatives were used as the partners. This method is green as it is catalyst-free, oxidant-free, and additive-free and shows atom-economy. This is the first example of an electrochemical reaction via cleavage of carbon-carbon triple bonds. Meanwhile, this is also the first example of a carbon-carbon triple bond cleavage reaction of alkynes with diols. This journal is
Selective Acylation of Aryl- A nd Heteroarylmagnesium Reagents with Esters in Continuous Flow
A selective acylation of readily accessible organomagnesium reagents with commercially available esters proceeds at convenient temperatures and short residence times in continuous flow. Flow conditions allow us to prevent premature collapse of the hemiacetal intermediates despite noncryogenic conditions, thus furnishing ketones in good yields. Throughout, the coordinating ability of the ester and/or Grignard was crucial for the reaction outcome. This was leveraged by the obtention of several bisaryl ketones using 2-hydroxy ester derivatives as substrates.
Heinz, Benjamin,Djukanovic, Dimitrije,Ganiek, Maximilian A.,Martin, Benjamin,Schenkel, Berthold,Knochel, Paul
supporting information
p. 493 - 496
(2020/01/31)
Oxidation of acetals by dimethyldioxirane
Kinetic data (k2's, LFER and activation parameters) for the oxidation of a series of acetals by dimethyldioxirane to the corresponding esters in dried acetone are reported; the results are consistent with either a H-atom abstraction or direct insertion mechanism.
Baumstark,Kovac, Franci,Vasquez, Pedro C.
p. 9 - 12
(2007/10/03)
More Articles about upstream products of 444169-52-2