Cyanuric chloride, a useful reagent for macrocyclic lactonization
Six ω-hydroxy acids have been converted to macrocyclic lactones by treatment with cyanuric chloride and triethylamine in acetone at room temperature. The mechanism apparently involves activation of both the carboxyl and hydroxyl groups.
Venkataraman,Wagle
p. 1893 - 1896
(2007/10/02)
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