444809-36-3

Basic information

• Product Name: 4H-1,3-Benzodioxin,6-(2R)-oxiranyl-(9CI)
• Synonyms: 4H-1,3-Benzodioxin,6-(2R)-oxiranyl-(9CI)
• CAS NO: 444809-36-3
• Molecular Formula: C₁₀H₁₀O₃
• Molecular Weight: 178.1846
• Product Categories: PHENYL
• Mol File: 444809-36-3.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4H-1,3-Benzodioxin,6-(2R)-oxiranyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1,3-Benzodioxin,6-(2R)-oxiranyl-(9CI)(444809-36-3)
• EPA Substance Registry System: 4H-1,3-Benzodioxin,6-(2R)-oxiranyl-(9CI)(444809-36-3)

Safety Data

• Hazardous Substances Data: 444809-36-3(Hazardous Substances Data)

Upstream product

• 324556-98-1 (R)-(-)-2-bromo-1-(1,3-benzodioxan-6-yl) ethanol 
• 58200-38-7 6-ω-bromoacetyl-1,3-benzodioxane 

Downstream Products

• 444809-38-5 1-(4H-benzo[1,3]dioxin-6-yl)-2-[6-(4-phenyl-butoxy)-hexylamino]-ethanol 
• 89365-50-4 salmeterol 

Relevant articles and documents

A convenient stereoselective synthesis of (R)-(-)-denopamine and (R)-(-)-salmeterol

β-Adrenoreceptor agonists (R)-(-)-denopamine (R)-1 and (R)-(-)-salmeterol (R)-2 have been prepared in good overall yield and high enantioselectivity through a biotransformative pathway.

Microbial reduction of ω-bromoacetophenones in the presence of surfactants

Several ω-bromoacetophenone derivatives 6a-f were reduced to (R)-(-)-2-bromo-1-(phenyl/substituted phenyl) ethanol derivatives 7a-f with whole cell biocatalysts in good yields. The enantiomeric excesses were increased to 95% using an anionic surfactant under an inert atmosphere in an aqueous medium. Copyright (C) 2000 Elsevier Science Ltd.