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1(2H)-Isoquinolinone,8-fluoro-(9CI) is a chemical compound with the molecular formula C9H6FNO, belonging to the isoquinoline class of compounds. It features a fluorine atom attached at the eighth position, which may contribute to its unique properties and potential applications in various fields.

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  • 444898-84-4 Structure
  • Basic information

    1. Product Name: 1(2H)-Isoquinolinone,8-fluoro-(9CI)
    2. Synonyms: 8-fluoroisoquinolin-1-ol;8-Fluoroisoquinolin-1(2H)-one;8-fluoro-2H-isoquinolin-1-one;1(2H)-Isoquinolinone,8-fluoro-(9CI);8-fluoro-1,2-dihydroisoquinolin-1-one
    3. CAS NO:444898-84-4
    4. Molecular Formula: C9H6FNO
    5. Molecular Weight: 163.1484432
    6. EINECS: N/A
    7. Product Categories: HALIDE
    8. Mol File: 444898-84-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1(2H)-Isoquinolinone,8-fluoro-(9CI)(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1(2H)-Isoquinolinone,8-fluoro-(9CI)(444898-84-4)
    11. EPA Substance Registry System: 1(2H)-Isoquinolinone,8-fluoro-(9CI)(444898-84-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 444898-84-4(Hazardous Substances Data)

444898-84-4 Usage

Uses

Used in Organic Synthesis:
1(2H)-Isoquinolinone,8-fluoro-(9CI) is used as a building block in organic synthesis for the creation of more complex molecules. Its unique structure allows for the development of novel compounds with potential applications in various industries.
Used in Pharmaceutical Research:
1(2H)-Isoquinolinone,8-fluoro-(9CI) is used as a research compound in pharmaceutical research to explore its potential pharmacological activities. Its isoquinoline core and fluorine substitution may contribute to its biological activity, making it a promising candidate for the development of new drugs or therapeutic agents.
Used in the Synthesis of Fluoro-Substituted Isoquinolines:
1(2H)-Isoquinolinone,8-fluoro-(9CI) serves as a precursor for the synthesis of other fluoro-substituted isoquinoline derivatives. These derivatives may exhibit enhanced properties or activities compared to their non-fluorinated counterparts, making them valuable in various applications, such as drug development or as intermediates in chemical synthesis.
Used in Drug Development:
1(2H)-Isoquinolinone,8-fluoro-(9CI) has potential applications in the development of new drugs or biologically active compounds. Its unique structure and potential pharmacological activities make it a valuable starting point for designing and optimizing novel therapeutic agents.
However, it is important to note that further research is needed to fully understand the properties and potential uses of 1(2H)-Isoquinolinone,8-fluoro-(9CI). This will help to unlock its full potential and contribute to advancements in various fields.

Check Digit Verification of cas no

The CAS Registry Mumber 444898-84-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,4,8,9 and 8 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 444898-84:
(8*4)+(7*4)+(6*4)+(5*8)+(4*9)+(3*8)+(2*8)+(1*4)=204
204 % 10 = 4
So 444898-84-4 is a valid CAS Registry Number.

444898-84-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 8-fluoro-2H-isoquinolin-1-one

1.2 Other means of identification

Product number -
Other names 1(2h)-isoquinolinone,8-fluoro

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:444898-84-4 SDS

444898-84-4Downstream Products

444898-84-4Relevant articles and documents

SUBSTITUTED ARYLMETHYLUREAS AND HETEROARYLMETHYLUREAS, ANALOGUES THEREOF, AND METHODS USING SAME

-

, (2020/07/07)

The present invention includes substituted arylmethyl ureas and heteroarylmethyl-ureas, and compositions comprising the same, that can be used to treat or prevent hepatitis B virus (HBV) infections in a patient.

Synthesis of novel substituted isoquinolones

Briet, Nicolas,Brookes, Michael H,Davenport, Richard J,Galvin, Frances C.A,Gilbert, Philip J,Mack, Stephen R,Sabin, Verity

, p. 5761 - 5766 (2007/10/03)

A series of novel substituted isoquinolones have been synthesised. This has been achieved by two routes, either Curtius rearrangment of cinnamic acids or via an isoquinoline N-oxide.

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