445303-09-3

Basic information

• Product Name: 4-CHLORO-3-TRIFLUOROMETHYLPHENYLBORONIC ACID, PINACOL ESTER
• Synonyms: 2-[4-Chloro-3-(trifluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzotrifluoride;2-(4-chloro-3-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;4-CHLORO-3-TRIFLUOROMETHYLPHENYLBORONIC ACID, PINACOL ESTER;4-Chloro-3-trifluoromethylphenylboronic acid,pinacol;1,3,2-Dioxaborolane, 2-[4-chloro-3-(trifluoroMethyl)phenyl]-4,4,5,5-tetraMethyl-
• CAS NO: 445303-09-3
• Molecular Formula: C₁₃H₁₅BClF₃O₂
• Molecular Weight: 306.52
• Product Categories: Aryl;Organoborons;Trifluoromethyl
• Mol File: 445303-09-3.mol

Chemical Properties

• Boiling Point: 327.076°C at 760 mmHg
• Flash Point: 151.611°C
• Appearance: /
• Density: 1.237g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.471
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-CHLORO-3-TRIFLUOROMETHYLPHENYLBORONIC ACID, PINACOL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLORO-3-TRIFLUOROMETHYLPHENYLBORONIC ACID, PINACOL ESTER(445303-09-3)
• EPA Substance Registry System: 4-CHLORO-3-TRIFLUOROMETHYLPHENYLBORONIC ACID, PINACOL ESTER(445303-09-3)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• Hazardous Substances Data: 445303-09-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4-Chloro-3-trifluoromethylphenylboronic acid, pinacol ester is used as a reagent in cross-coupling reactions for the synthesis of pharmaceutical compounds. Its phenyltrifluoroborate functional group contributes to the development of complex molecular architectures, enabling the creation of diverse biologically active compounds with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 4-chloro-3-trifluoromethylphenylboronic acid, pinacol ester is utilized as a reagent for the synthesis of agrochemical compounds. Its unique functional group aids in the development of complex molecular structures, which can be used to create effective and targeted agrochemical products for crop protection and other agricultural applications.
Used in Organic Synthesis:
4-Chloro-3-trifluoromethylphenylboronic acid, pinacol ester is employed as a versatile reagent in organic synthesis for the construction of complex molecular architectures. Its stability and ease of handling make it an ideal building block for the synthesis of a wide range of biologically active compounds, contributing to the advancement of chemical research and development.

InChI:InChI=1/C13H15BClF3O2/c1-11(2)12(3,4)20-14(19-11)8-5-6-10(15)9(7-8)13(16,17)18/h5-7H,1-4H3

Upstream product

• 445-01-2 5-bromo-2-chlorobenzotrifluoride 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 1007882-60-1 C₁₉H₂₁ClF₃N₃O₂ 
• 1737-36-6 4-chloro-3-(trifluoromethyl)benzoic acid 
• 1007882-60-1 C₁₉H₂₁ClF₃N₃O₂ 

Relevant articles and documents

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