Oxidative reactions of azines. 2. Synthesis and molecular structure of 3,4-dihydroxy-1-methyl-2-oxo-4-(γ-pyridyl)piperidine
The oxidative ketodihydroxylation of a 1,2,3,6-tetrahydropyridine is reported. Using PMR and x-ray structural analysis, the product was shown to be 3,4-dihydroxy-1-methyl-2-oxo-4-(γ-pyridyl)piperidine. 1997 Plenum Publishing Corporation.
Oxidative reactions of azines. 6. Lactamization of 4-aryl- and 4-phenethenyl-substituted 1,2,3,6-tetrahydropyridines and dihydroxylation of 4-aryl-1,2,5,6-tetrahydropyrid-2-ones using potassium permanganate
Oxidation of 4-phenyl-, 4-(4-pyridyl)-, and 4-phenethenyl-1,2,3,6-tetrahydropyridines with potassium permanganate can stop at the stage of the introduction of an oxo group into the allyl C(2) position of the piperideine fragment. In contrast to
Oxidative reactions of azines 5.* ketodihydroxylation and coupling of 4-(γ-pyridyl)-1,2,5,6-tetrahydropyridines with acetone. Molecular and crystal structure of 3,4-dihydroxy-4-(γ-pyridyl)-1-ethylpiperidin-2-one
Oxidative coupling of 1-alkyl(benzyl)-4-(γ-pyridyl)-1,2,5,6-tetrahydropyridines with acetone in the presence of KMnO4 follows two pathways and yields both 1-R-2-(acetylmethylene)tetrahydropyridines and 1-R-3,4-dihydroxypiperidin-2-ones. When ac