- Semisynthetic fluorescent sensor proteins based on self-labeling proteintags
-
Genetically encoded fluorescent sensor proteins offer the possibility toprobe the concentration of key metabolites in living cells. The approac hes currently used to generate such fluorescent sensor proteins lack generality, as they require a protein that
- Brun, Matthias A.,Tan, Kui-Thong,Nakata, Eiji,Hinner, Marlon J.,Johnsson, Kai
-
supporting information; experimental part
p. 5873 - 5884
(2009/09/24)
-
- Thermolysis of Polyazapentadienes. Part 6. Gas-phase Cyclisation of 1,5-Diaryl-1,5-diazapentadienes: Mechanistic Aspects and some Synthetic Applications
-
The mode of formation of quinolines by gas-phase pyrolysis of 1,5-diaryl-1,5-diazapentadienes is contrasted with the thermal behaviour of 1,2,5-triazapentadienes.The mechanism involves concerted ring closure followed by a rapid 1,5-hydrogen shift to give a 3,4-dihydroquinoline intermediate, e.g. (19) or (21).Subsequent aromatisation takes place by a stepwise, free-radical process.Methylquinolines (9), (10), (12), and (13) were obtained on a preparative scale by this method.
- McNab, Hamish,Murray, M. Elizabeth-Ann
-
p. 1565 - 1568
(2007/10/02)
-