Copper(I)-catalyzed synthesis of substituted 2-mercapto benzimidazoles
An efficient method for the preparation of various substituted 2-mercapto benzimidazoles from their corresponding thioureas has been developed. 5-Alkylation of thioureas followed by Cu-catalyzed intramolecular N-arylation furnished substituted 2-mercapto
Murru, Siva,Patel, Bhisma K.,Le Bras, Jean,Muzart, Jacques
experimental part
p. 2217 - 2220
(2009/07/01)
DIKETO-PIPERAZINE AND PIPERIDINE DERIVATIVES AS ANTIVIRAL AGENTS
This disclosure provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the disclosure is concerned with diketo piperazine and piperadine derivatives that possess unique antiviral activity. More particularly, the present disclosure relates to compounds useful for the treatment of HIV and AIDS.
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Page/Page column 20-21; 34
(2008/06/13)
Synthesis, structure, and tautomerism of formazans that contain 1-aryl-2-benzimidazolyl residues
1,5-Bis(1-aryl-2-benzimidazolyl)-3-methyl- and 1-(p-tolyl)-3-methyl-5-(1-aryl-2-benzimidazolyl)formazans were synthesized. It was shown by IR spectroscopy (from the change in the spectral characteristics of the NH, groups) that the formazans exist in the
Tyurenkova,Mudretsova,Mertsalov,Bednyagina
p. 637 - 640
(2007/10/02)
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