452085-30-2

Basic information

• Product Name: C₅₀H₇₈O₅Si₂
• Synonyms: C₅₀H₇₈O₅Si₂
• CAS NO: 452085-30-2
• Molecular Weight: 815.337
• Mol File: 452085-30-2.mol

Chemical Properties

• CAS DataBase Reference: C₅₀H₇₈O₅Si₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₅₀H₇₈O₅Si₂(452085-30-2)
• EPA Substance Registry System: C₅₀H₇₈O₅Si₂(452085-30-2)

Safety Data

• Hazardous Substances Data: 452085-30-2(Hazardous Substances Data)

Upstream product

• 100791-67-1 (2R,3S)-1,2-O-isopropylidene-hexane-1,2,3-triol 
• 79364-35-5 (S)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)but-3-en-1-ol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 452085-27-7 (2R,3S)-3-O-benzylhexane-1,2,3-triol 
• 452085-28-8 (S)-2-Benzyloxy-pentanal 
• 452085-20-0 (3R,4R,5R)-8-Benzyloxy-4-methyl-oct-1-ene-3,5-diol 
• 1026870-22-3 tert-Butyl-[(S)-2-((2R,5S)-5-{(R)-1-[(4R,5R,6R)-6-(3-iodo-propyl)-2,2,5-trimethyl-[1,3]dioxan-4-yl]-ethyl}-tetrahydro-furan-2-yl)-propoxy]-diphenyl-silane 
• 452085-21-1 [(S)-2-((2R,5S)-5-{(R)-[(4S,5R,6R)-6-(3-Benzyloxy-propyl)-2,2,5-trimethyl-[1,3]dioxan-4-yl]-iodo-methyl}-tetrahydro-furan-2-yl)-propoxy]-tert-butyl-diphenyl-silane 

Downstream Products

• 452085-32-4 ((S)-2-{(2R,5S)-5-[(1R,2S,3R)-3-[(2R,5S)-5-((R)-2-Azido-pentyl)-tetrahydro-furan-2-yl]-2-(4-methoxy-benzyloxy)-1-methyl-butyl]-tetrahydro-furan-2-yl}-propoxy)-tert-butyl-diphenyl-silane 
• 452085-31-3 (S)-1-[(2S,5R)-5-((1S,2S,3S)-3-{(2S,5R)-5-[(S)-2-(tert-Butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-tetrahydro-furan-2-yl}-2-hydroxy-1-methyl-butyl)-tetrahydro-furan-2-yl]-pentan-2-ol 

Relevant articles and documents

A stereocontrolled synthetic route to the C1-C18 subunit of pamamycin-607

The C1-C18 subunit 2 of the 16-membered macrodiolide pamamycin-607 has been synthesized stereoselectively using the Ag2CO3-mediated intramolecular iodoetherification for the two cis-2,5-disubstituted tetrahydrofurans, crotylation and cuprate epoxide opening for the hydroxyl and methyl substituents.