452323-86-3 Usage
General Description
The chemical 1,2,4-Triazolo[4,3-c]pyrimidin-5(6H)-one,3,8-dimethyl-(9CI) is a heterocyclic compound with a unique structure and chemical properties. It is a derivative of pyrimidine and contains a triazolopyrimidine ring system. The compound is also known as alprazolam, a medication used for the treatment of anxiety disorders and panic attacks. It works by affecting the chemicals in the brain that may be unbalanced in people with anxiety. Alprazolam is classified as a benzodiazepine and acts on the central nervous system to produce a calming effect. However, it is important to use this medication under the guidance of a healthcare professional and to be aware of its potential for addiction and dependence.
Check Digit Verification of cas no
The CAS Registry Mumber 452323-86-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,5,2,3,2 and 3 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 452323-86:
(8*4)+(7*5)+(6*2)+(5*3)+(4*2)+(3*3)+(2*8)+(1*6)=133
133 % 10 = 3
So 452323-86-3 is a valid CAS Registry Number.
452323-86-3Relevant articles and documents
The first reliable, general synthesis of the 5-oxo derivatives of 5,6-dihydro-1,2,4-triazolo[4,3-c]-pyrimidine and the rates of isomerization of the [4,3-c] compounds into their [1,5-c] isomers
Nagamatsu, Tomohisa,Fujita, Takayuki
, p. 631 - 636 (2007/10/03)
This paper describes a reliable synthesis of the 5-oxo derivatives (8) of 5,6-dihydro-1,2,4-triazolo[4,3-c]pyrimidine, by the reaction of 2-oxo-1,2-dihydropyrimidin-4-ylhydrazines (7) with the appropriate triethyl orthoesters in trifluoroacetic acid below 30°C or by the oxidative cyclization of their aldehyde hydrazones (10) with 70% nitric acid in trifluoroacetic acid below 40°C, and the rates of isomerization of the [4,3-c] compounds (8) into the [1,5-c] isomers (9).
