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6-Bromo-2-(4-methoxyphenyl)imidazo[1,2-a]pyridine is a heterocyclic organic compound characterized by its unique molecular formula C14H11BrN2O. It belongs to the class of imidazo[1,2-a]pyridines and features a bromine atom, a methoxy group, and a phenyl ring within its structure. This chemical compound holds promise in pharmaceutical research and drug development, particularly for the synthesis of novel bioactive compounds. Ongoing studies in chemistry and pharmacology are delving into its specific properties and potential applications.

452967-40-7

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452967-40-7 Usage

Uses

Used in Pharmaceutical Research and Drug Development:
6-Bromo-2-(4-methoxyphenyl)imidazo[1,2-a]pyridine is utilized as a key intermediate in the synthesis of new bioactive compounds. Its unique structure, which includes a bromine atom, a methoxy group, and a phenyl ring, contributes to its potential as a precursor for developing innovative pharmaceutical agents.
Used in Chemical Synthesis:
In the chemical synthesis industry, 6-Bromo-2-(4-methoxyphenyl)imidazo[1,2-a]pyridine serves as a valuable building block for creating a variety of complex organic molecules. Its presence in the synthesis process can lead to the development of new compounds with diverse applications across different fields.
Used in Medicinal Chemistry:
6-Bromo-2-(4-methoxyphenyl)imidazo[1,2-a]pyridine is employed as a scaffold in medicinal chemistry for the design and optimization of drug candidates. Its structural features allow for modifications that can enhance the pharmacological properties of potential therapeutic agents.
Note: The specific applications and industries for 6-Bromo-2-(4-methoxyphenyl)imidazo[1,2-a]pyridine are not explicitly mentioned in the provided materials. The uses listed above are inferred based on its potential role in pharmaceutical research, drug development, and chemical synthesis. Further research and exploration are necessary to fully understand its applications across various industries.

Check Digit Verification of cas no

The CAS Registry Mumber 452967-40-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,5,2,9,6 and 7 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 452967-40:
(8*4)+(7*5)+(6*2)+(5*9)+(4*6)+(3*7)+(2*4)+(1*0)=177
177 % 10 = 7
So 452967-40-7 is a valid CAS Registry Number.
InChI:InChI=1/C14H11BrN2O/c1-18-12-5-2-10(3-6-12)13-9-17-8-11(15)4-7-14(17)16-13/h2-9H,1H3

452967-40-7Downstream Products

452967-40-7Relevant articles and documents

Identification of novel SIRT1 activators endowed with cardioprotective profile

Brogi, Simone,Calderone, Vincenzo,Flori, Lorenzo,La Motta, Concettina,Petrarolo, Giovanni,Testai, Lara

, (2021/07/21)

Drugs targeting epigenetic mechanisms are attracting the attention of scientists since it was observed that the modulation of this post-translational apparatus, could help to identify innovative therapeutic strategies. Among the epigenetic druggable targe

Imidazo[1,2- a]pyridine derivatives as aldehyde dehydrogenase inhibitors: Novel chemotypes to target glioblastoma stem cells

Quattrini, Luca,Gelardi, Edoardo Luigi Maria,Coviello, Vito,Sartini, Stefania,Ferraris, Davide Maria,Mori, Mattia,Nakano, Ichiro,Garavaglia, Silvia,La Motta, Concettina

, p. 4603 - 4616 (2020/06/08)

Glioblastoma multiforme (GBM) is the deadliest form of brain tumor. It is known for its ability to escape the therapeutic options available to date thanks to the presence of a subset of cells endowed with stem-like properties and ability to resist to cyto

Oxidative Cross-Coupling of sp3- and sp2-Hybridized C-H Bonds: Vanadium-Catalyzed Aminomethylation of Imidazo[1,2-a]pyridines

Kaswan, Pinku,Porter, Ashley,Pericherla, Kasiviswanadharaju,Simone, Marissa,Peters, Sean,Kumar, Anil,Deboef, Brenton

supporting information, p. 5208 - 5211 (2015/11/18)

The vanadium-catalyzed oxidative coupling of substituted 2-arylimidiazo[1,2-a]pyridines to N-methylmorpholine oxide, which acts as both a coupling partner and an oxidant, has been achieved. This reaction was applied to various substituted imidiazo[1,2-a]pyridine and indole substrates, resulting in yields as high as 90%. Mechanistic investigations indicate that the reaction may proceed via a Mannich-type process. This work demonstrates how oxidative aminomethylation can be used as a useful method to introduce tertiary amines into heterocycles, thus providing an alternative method for conventional Mannich-type reactions.

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