464180-72-1

Basic information

• Product Name: 1H-Pyrrolo[2,3-b]pyridine,1,3-dimethyl-
• Synonyms: 1H-Pyrrolo[2,3-b]pyridine,1,3-dimethyl-;1H-Pyrrolo[2,3-b]pyridine,1,3-dimethyl-(9CI)
• CAS NO: 464180-72-1
• Molecular Formula: C9H10N2
• Molecular Weight: 146.1891
• Product Categories: AMINETERTIARY;PYRIDINE
• Mol File: 464180-72-1.mol

Chemical Properties

• Boiling Point: 275.5°C at 760 mmHg
• Flash Point: 120.4°C
• Appearance: /
• Density: 1.09g/cm³
• Vapor Pressure: 0.00855mmHg at 25°C
• Refractive Index: 1.595
• CAS DataBase Reference: 1H-Pyrrolo[2,3-b]pyridine,1,3-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolo[2,3-b]pyridine,1,3-dimethyl-(464180-72-1)
• EPA Substance Registry System: 1H-Pyrrolo[2,3-b]pyridine,1,3-dimethyl-(464180-72-1)

Safety Data

• Hazardous Substances Data: 464180-72-1(Hazardous Substances Data)

Usage

Heterocyclic compound

Consists of a pyrrole ring fused to a pyridine ring This means that the compound is made up of a ring of atoms with at least one nitrogen atom, which gives it unique chemical properties.

Methyl groups attached at the 1 and 3 positions

The pyrrole ring has two methyl groups (CH3) attached to it at specific positions, which affects its chemical reactivity and properties.

Building block in synthesis

Commonly used in the synthesis of pharmaceuticals and organic compounds This means that 1H-Pyrrolo[2,3-b]pyridine,1,3-dimethylis a key component in the creation of other, more complex molecules.

Potential applications in medicinal chemistry

May have potential uses in the development of new drugs and therapies This means that the compound could be useful in the future for treating diseases and improving human health.

Used in research and development

Used in research and development laboratories for studies and experiments related to organic chemistry and chemical synthesis This means that the compound is an important tool for scientists who are studying the properties and behavior of organic molecules.

InChI:InChI=1/C9H10N2/c1-7-6-11(2)9-8(7)4-3-5-10-9/h3-6H,1-2H3

Upstream product

• 5654-93-3 3-methyl-1H-pyrrolo<2,3-b>pyridine 
• 74-88-4 methyl iodide 
• 4649-09-6 1H-pyrrolo[2,3-b]pyridin-3-carbaldehyde 
• 464180-71-0 C₉H₉N₅O 

Relevant articles and documents

Excited-state double-proton transfer on 3-methyl-7-azaindole in a single crystal: Deuterium isotope/tunneling effect

Unlike 7-azaindole consisting of the tetrameric configuration, 3-methyl-7-azaindole (3MAI) exists solely as intact double hydrogen-bonded dimeric forms in a single crystal. Both steady-state and time-resolved measurements down to 8.0 K reveal remarkable deuterium isotope effects on the rate of excited-state double proton transfer (ESDPT) in the N(1)-deuterated 3MAI (3MAI-d) single crystal. The rates of ESDPT for the 3MAI-d dimer resolved at 150 K are mainly governed by the proton tunneling mechanism. At 12 K, the nearly temperature-independent ESDPT dynamics lead us to qualitatively deduce a barrier height of ～ 1.73 kcal/mol for the 3MAI-d dimer. The results provide an ideal model to investigate the intrinsic ESDPT dynamics for 7-azaindole analogues in which the structural information is well documented.