- Benzobutyrolactone derivatives, synthetic method and application thereof in preparation of bactericides
-
The invention discloses benzobutyrolactone derivatives, a synthetic method and application thereof in preparation of bactericides. The method comprises the following steps: taking sesquiterpene lactone pharmacophore alpha-methylene-gamma-butyrolactone as a lead compound, integrating benzofuranone pharmacophore, modifying at an alpha-methylene position, and performing directional derivative synthesis to obtain a series of alpha-alkenylene benzobutyrolactone compounds. The antibacterial activities of the compounds are determined, and two high-activity compounds with excellent industrialization development prospects are synthesized on the structure-effect basis. The compounds are used for controlling plant diseases caused by pathogenic bacteria such as wheat powdery mildew, wheat scab, take-all disease of wheat, wheat sharp eyespot, corn northern leaf blight, rice sheath blight disease, rice blast, cotton damping-off, phytoph-thora capsici leonian, botrytis cinerea, tomato leaf mould, tomato early/late blight, cucumber anthracnose, fusarium wilt of cucumber, sclerotinia rot of colza and the like.
- -
-
Paragraph 0041; 0042; 0043; 0044; 0045
(2018/04/03)
-
- Synthesis of Vinyl Carboxylic Acids using Carbon Dioxide as a Carbon Source by Iron-Catalyzed Hydromagnesiation
-
An iron-catalyzed synthesis of α,β-unsaturated carboxylic acids from alkynes and carbon dioxide was developed. This reaction proceeds through hydromagnesiation of alkynes followed by carbon dioxide insertion under atmospheric pressure and ambient temperature in the presence of iron and a Grignard reagent as a catalyst and hydride source, respectively. Several symmetrical and unsymmetrical alkynes were transformed into the corresponding acids in good to excellent yields. The methodology provides an efficient route to the synthesis of vinyl carboxylic acids.
- Santhoshkumar, Rajagopal,Hong, Ya-Chun,Luo, Ching-Zong,Wu, Yun-Ching,Hung, Chen-Hsun,Hwang, Kuen-Yuan,Tu, An-Pang,Cheng, Chien-Hong
-
p. 2210 - 2213
(2016/07/19)
-
- Palladium-catalyzed hydrophenoxycarbonylation of internal alkynes by phenol and CO: The use of Zn for the formation of active catalyst
-
The palladium-catalyzed hydrophenoxycarbonylation of internal alkynes by phenol and carbon monoxide was successfully realized by Pd(OAc)2/dppp catalyst system in the co-presence of Zn dust.
- Kuniyasu, Hitoshi,Yoshizawa, Takahiro,Kambe, Nobuaki
-
scheme or table
p. 6818 - 6821
(2011/03/17)
-
- 2-(2-Hydroxyaryl)cinnamic amides: a new class of axially chiral molecules
-
The syntheses of several differently substituted amides formally derived from a chiral amine, either E-2-(2-hydroxyphenyl)cinnamic acid or both E- and Z-2-(2-hydroxynaphthyl)cinnamic acid, are reported. These molecules display a restricted rotation about
- Marelli, Chiara,Monti, Chiara,Galli, Simona,Masciocchi, Norberto,Piarulli, Umberto
-
p. 8943 - 8951
(2007/10/03)
-
- An ionic O → α- and β-vinyl carbamoyl translocation of 2-(O-carbamoyl) stilbenes
-
(Equation Presented) New anionic oxygen to α- and β-vinyl carbamoyl migration reactions, 17a and 26a-c → 18 and 30a-c, proceed under LDA-mediated conditions leading stereoselectively to highly substituted stilbenes bearing electron-donating and -withdrawing substituants. Compounds 17a and 26a-c are prepared by combination of efficient, directed ortho metalation, Sonogashira, and Suzuki-Miyaura cross-coupling procedures.
- Reed, Mark A.,Chang, Michelle T.,Snieckus, Victor
-
p. 2297 - 2300
(2007/10/03)
-
- Reactions of Halogenated α-Phenylcinnamic Acids with Potassium Amide in Liquid Ammonia : Part II - Mechanism of Cyclisation of ortho- and meta- Chloro-α-phenylcinnamic Acids
-
Reaction of trans-2-chloro-3-methoxy-α-phenylcinnamic acid (1) with KNH2/NH3 gives 4-methoxyphenanthrene-9-carboxylic acid (2).A similar treatment of 1-(2'-chlorophenyl)-2,2-diphenylethylene (15a) affords 9-phenylphenanthrene but its meta-halogenated anal
- Kessar, S. V.,Nadir, U. K.,Pahwa, P. S.,Singh, Paramjit,Gupta, Y. P.
-
-