- Triterpene saponins of Maesa lanceolata leaves
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Chemical investigation of Maesa lanceolata leaves aqueous MeOH extract has led to the isolation of eight new triterpene glycosides identified as 16-oxo-28-hydroxyolean-12-ene 3-O-β-glucopyranosyl-(1''→6')-β- glucopyranoside 1, 16α, 28-dihydroxyolean-12-ene 3-O-β-[(6"-O- galloylglucopyranosyl-(1"→2')][β-glucopyranosyl-(1'''→6')] -β-glucopyranoside 2, 16α, 22α, 28-trihydroxyolean-12-ene 3-O-[β-glucopyranosyl-(1"→2')] [α-rhamnopyranosyl- (1'''→6']-β-glucopyranoside 3, 22α-acetyl-16α- hydroxyolean-12-en-28-al 3-O-[α-rhamnopyranosyl- (1""→6"')-β-glucopyranosyl-(1"'→3')] [β-glucopyranosyl-(1"→2')]-β-arabinopyranoside 4, 22α-acetyl-16α,21 β-dihydroxyoleanane-13β:28-olide 3-O-[β-glucopyranosyl-(1'''→6')] [6''-O-coumaroylglucopyranosyl- (1''→2')]-β-glucopyranoside 5, 16α,22α-diacetyl-21β- angeloyloleanane-13β:28-olide 3 β-O-[β-glucopyranosyl- (1''→2')][β-glucopyranosyl-(1'''→4')]-β-glucopyranoside 6, 16α, 22α, 28-trihydroxy-21β-angeloyloleanan-12-ene 3 β-O-[α-rhamnopyranosyl-(1'''→6'')][β-glucopyranosyl- (1''→2')]-β-xylopyranoside 7, 16α, 28-dihydroxy-22α- acetyl-21β-angeloylolean-12-ene 3-O-[β-galactopyranosyl- (1"→2')] [α-rhamnopyranosyl-(1'"→4')]-α- arabinopyranoside 8. Together with these were known compounds quercetin, myricetin, quercetin 3-O-rhamnopyranoside, myricetin 3-O-β-glucopyranoside, gallic acid, sistosterol 3-O-β-glucopyranoside, rutin, myricetin 3-O-α-rhamnopyranosyl-(1"→3')-β-glucopyranoside and quercetin 3,7-O-β-diglucopyranoside. Their structures were determined using spectroscopic methods as well as comparison with data from known compounds. The in vitro antibacterial activity of aqueous MeOH extract of the leaves of M. lanceolata was also investigated and zones of inhibition ranging from 28±0.1 to 10±0.2 mm were observed. The minimum inhibitory concentration (MIC) for the extract ranged between 100 to 1000 μg/ml with the highest activity being observed with Vibro cholerae. Among the pure isolates, compound 6 was the most active and its highest recorded MIC value was 62.5 μg/ml against V. cholerae. ARKAT-USA, Inc.
- Manguro, Lawrence Onyango A.,Midiwo, Jacob O.,Tietze, Lutz F.,Hao, Pang
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experimental part
p. 172 - 198
(2011/06/09)
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- SAPONINS IN CYCLAMEN SPECIES: CONFIGURATION OF CYCLAMIRETIN C AND STRUCTURE OF ISOCYCLAMIN
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Five sapogenins and three saponins were identified in bulbs of 14 cytologically defined Cyclamen species and their structures were determined by means of mass, 1H and 13C NMR spectroscopy.In addition to the known products of hydrolysis, primulagenin A was found, and cyclamiretin C was shown to be identical with cyclamigenin C.The new saponin isocyclamin was identified as 3β--O-β-D-glucopyranosyl-(1-4)--α-L-arabinopyranosyl>-16α-hydroxy-13β,28-epoxy-olean-30-al. - Key Word Index - Cyclamen; Primulaceae; saponin; sapogenin; chemotaxonomy.
- Reznicek, Gottfried,Jurenitsch, Johann,Robien, Wolfgang,Kubelka, Wolfgang
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p. 825 - 828
(2007/10/02)
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- Triterpenoid Glycosides of Corchorus acutangulus Lam.
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Four new triterpenoid glycosides, corchorusins A,B,C, and D, isolated from the aerial part of Corchorus acutangulus Lam. were respectively defined as longispinogenin 3-O-β-D-galactopyranoside (1), saikogenin F 3-O-β-D-galactopyranoside (12), 23-hydroxylongispinogenin 3-O-β-D-galactopyranoside (6), and saikogenin E 3-O-β-D-glucopyranosyl(12)-β-D-galactopyranoside (15) based on their spectral properties and some chemical transformations.
- Mahato, Shashi B.,Pal, Bikas C.
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p. 629 - 634
(2007/10/02)
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- THE STRUCTURE OF PROSAPOGENIN OBTAINED FROM THE SAPONIN OF GLEDITSIA JAPONICA
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Key Word Index - Gleditsia japonica; Leguminosae; saponins; bisdesmoside; echinocystic acid derivatives; Gleditsia saponin C. Prosapogenin was obtained by alkaline hydrolysis of Gleditsia saponin GS-C (echinocystic acid 3,28-O-bisdesmoside), a new triterpenoid saponin isolated from Gleditsia japonica.Prosapogenin was shown on the basis of chemical and physicochemical data to be echinocystic acid 3-O-β-D-xylopyranosyl-(1-2)-α-L-arabinopyranosyl-(1-6)-β-D-glucopyranoside.
- Konoshima, Takao,Fukushima, Hiroyuki,Inui,Hideo,Sato, Keiko,Sawada, Tokunosuke
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p. 139 - 142
(2007/10/02)
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