Solid-phase enzymatic synthesis of oligonucleotides.
[formula: see text] The controlled and selective synthesis of oligonucleotides on the solid phase is possible under mild aqueous conditions using the enzyme T4 RNA ligase, the resins being tentagel or kieselguhr/polydimethylacrylamide.
Schmitz,Reetz
p. 1729 - 1731
(2008/02/11)
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