ISOINDOLINONE AND PYRROLOPYRIDINONE DERIVATIVES AS AKT INHIBITORS
The present invention provides isoindolinone and pyrrolopyridinone derivatives, as well as their compositions and methods of use, that inhibit the activity of the serine/threonine kinase, Akt, and are useful in the treatment of diseases related to the act
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Paragraph 0205
(2013/04/24)
Imidazole based kinase inhibitors
The present invention provides compounds having Formula I and their use for the treatment of cancer.
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Page/Page column 10
(2008/06/13)
Benzimidazole C-2 heterocycles as kinase inhibitors
Benzimidazole derivatives having the general formula I are provided. These compounds are useful as tyrosine kinase inhibitors, especially for the treatment of cancer.
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Page/Page column 13
(2010/02/11)
NOVEL TYROSINE KINASE INHIBITORS
The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof. The formula (I) compounds inhibit tyrosine kinase enzymes thereby making them useful as anti-cancer agents.
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Page 37
(2008/06/13)
Novel tyrosine kinase inhibitors
The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase enzymes thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases which can be treated by inhibiting tyrosine kinase enzymes.
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Page 22
(2010/11/30)
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