Welcome to LookChem.com Sign In|Join Free

CAS

  • or

474-48-6

Reserpin N-oxide is a natural alkaloid and an active metabolite of reserpine, an indole alkaloid derived from the plant Rauwolfia serpentina. It possesses a tetracyclic alkaloid ring system with functional groups that contribute to its pharmacological effects. Reserpin N-oxide is known for its sedative and antipsychotic properties, making it a valuable compound in the treatment of high blood pressure, anxiety, and mental disorders such as schizophrenia.

474-48-6 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

  • Yohimban-16-carboxylicacid, 11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester,4-oxide, (3b,16b,17a,18b,20a)- (9CI)

    Cas No: 474-48-6

  • USD $ 100.0-100.0 / Gram

  • 1 Gram

  • 10 Metric Ton/Day

  • HENAN NEW BLUE CHEMICAL CO.,LTD
  • Contact Supplier
  • 474-48-6 Structure

  • Basic information

    1. Product Name: Reserpin N-oxide
    2. Synonyms: (3β,20α)-11,17α-Dimethoxy-18β-[(3,4,5-trimethoxybenzoyl)oxy]-16β-(methoxycarbonyl)yohimban 4-oxide;(3β,20α)-16β-(Methoxycarbonyl)-11,17α-dimethoxy-18β-[(3,4,5-trimethoxybenzoyl)oxy]yohimban 4-oxide;Renoxidine;Renoxydine;Reserpin N-oxide;Reserpoxidine;(3beta,16beta,17alpha,18beta,20alpha)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-yohimban-16-carboxylic acid methyl ester 4-oxide;Reserpine N-oxide
    3. CAS NO:474-48-6
    4. Molecular Formula: C33H40N2O10
    5. Molecular Weight: 624.6781
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 474-48-6.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Reserpin N-oxide(CAS DataBase Reference)
    10. NIST Chemistry Reference: Reserpin N-oxide(474-48-6)
    11. EPA Substance Registry System: Reserpin N-oxide(474-48-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 474-48-6(Hazardous Substances Data)

474-48-6 Usage

Uses

Used in Pharmaceutical Industry:
Reserpin N-oxide is used as a sedative and antipsychotic medication for the treatment of high blood pressure, anxiety, and mental disorders such as schizophrenia. It functions by acting on the central nervous system to decrease the levels of neurotransmitters, particularly dopamine and norepinephrine, which helps regulate mood and behavior.
Used in Neurotransmitter Regulation:
Reserpin N-oxide is used as a neurotransmitter regulator to decrease the levels of certain neurotransmitters, such as dopamine and norepinephrine, in the central nervous system. This action helps in managing mood and behavior, making it a potential candidate for the treatment of mental disorders.

Check Digit Verification of cas no

The CAS Registry Mumber 474-48-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,7 and 4 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 474-48:
(5*4)+(4*7)+(3*4)+(2*4)+(1*8)=76
76 % 10 = 6
So 474-48-6 is a valid CAS Registry Number.

474-48-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 11,17-dimethoxy-4-oxy-18-(3,4,5-trimethoxy-benzoyloxy)-yohimbane-16-carboxylic acid methyl ester

1.2 Other means of identification

Product number -
Other names ent-11,17β-dimethoxy-4-oxy-18α-(3,4,5-trimethoxy-benzoyloxy)-15β-yohimban-16α-carboxylic acid methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:474-48-6 SDS

474-48-6Upstream product

474-48-6Downstream Products

474-48-6Relevant articles and documents

Indole cleavage with mebhydroline by sodium periodate. Part 1: Basic substituted indoles

Moehrle,Nestle,Westle

, p. 741 - 748 (2007/10/03)

The reaction behaviour of yohimbine (1), reserpine (5) and mebhydroline (7) as basic substituted indoles against periodate was examined. While 1 and 5 gave only the corresponding amine oxides 2 resp. 6 as definitive products, resulted from 7 beside the N-

Indole cleavage with mebhydroline by sodium periodate: Part 1: Basic substituted indoles

Moehrle,Nestle,Westle

, p. 445 - 452 (2007/10/03)

The reaction behaviour of yohimbine (1), reserpine (5) and mebhydroline (7) as basic substituted indoles against periodate was examined. While 1 and 5 gave only the corresponding amine oxides 2 resp. 6 as definitive products, resulted from 7 beside the N-oxide 8 and stepwise dehydrogenation of the tetrahydro-γ-carboline to 9 and 13 also an attack at the indole system. In this ring contractions led to the spiro compounds 10 and 12 and with ring cleavage and loss of a C-1-unit the dilactam 11 was created.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 474-48-6