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3-amino-N,N-diethyl-4-nitrobenzamide is a chemical compound with the molecular formula C13H17N3O3. It is an organic compound that belongs to the class of benzamides, which are derivatives of benzoic acid. 3-amino-N,N-diethyl-4-nitrobenzamide contains an amino group, two ethyl groups, and a nitro group attached to a benzene ring. It is commonly used in organic synthesis and pharmaceutical research as a reagent and intermediate for the production of various pharmaceuticals and organic compounds. Due to its structural properties, it may also have potential applications in medicinal chemistry and drug development.

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  • 474020-77-4 Structure
  • Basic information

    1. Product Name: 3-amino-N,N-diethyl-4-nitrobenzamide
    2. Synonyms: 3-amino-N,N-diethyl-4-nitrobenzamide
    3. CAS NO:474020-77-4
    4. Molecular Formula: C11H15N3O3
    5. Molecular Weight: 237.258
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 474020-77-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 465.36 °C at 760 mmHg
    3. Flash Point: 235.242 °C
    4. Appearance: /
    5. Density: 1.237 g/cm3
    6. Vapor Pressure: 0mmHg at 25°C
    7. Refractive Index: 1.589
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 3-amino-N,N-diethyl-4-nitrobenzamide(CAS DataBase Reference)
    11. NIST Chemistry Reference: 3-amino-N,N-diethyl-4-nitrobenzamide(474020-77-4)
    12. EPA Substance Registry System: 3-amino-N,N-diethyl-4-nitrobenzamide(474020-77-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 474020-77-4(Hazardous Substances Data)

474020-77-4 Usage

Uses

Used in Organic Synthesis:
3-amino-N,N-diethyl-4-nitrobenzamide is used as a reagent in organic synthesis for the production of various organic compounds. Its unique structure allows for versatile chemical reactions, making it a valuable component in the synthesis of a wide range of molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 3-amino-N,N-diethyl-4-nitrobenzamide is used as an intermediate in the production of various pharmaceuticals. Its presence in the synthesis process contributes to the development of new drugs and medicines.
Used in Medicinal Chemistry:
3-amino-N,N-diethyl-4-nitrobenzamide is used as a structural component in medicinal chemistry. Its unique arrangement of functional groups allows for the exploration of new chemical pathways and interactions, which can lead to the discovery of novel therapeutic agents.
Used in Drug Development:
Due to its potential applications in medicinal chemistry, 3-amino-N,N-diethyl-4-nitrobenzamide is also used in drug development. Its structural properties make it a promising candidate for the design and development of new pharmaceuticals with improved efficacy and safety profiles.

Check Digit Verification of cas no

The CAS Registry Mumber 474020-77-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,4,0,2 and 0 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 474020-77:
(8*4)+(7*7)+(6*4)+(5*0)+(4*2)+(3*0)+(2*7)+(1*7)=134
134 % 10 = 4
So 474020-77-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H15N3O3/c1-3-13(4-2)11(15)8-5-6-10(14(16)17)9(12)7-8/h5-7H,3-4,12H2,1-2H3

474020-77-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-amino-N,N-diethyl-4-nitrobenzamide

1.2 Other means of identification

Product number -
Other names I01-9391

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:474020-77-4 SDS

474020-77-4Downstream Products

474020-77-4Relevant articles and documents

Novel benzimidazole derivatives as selective CB2 agonists

Pagé, Daniel,Balaux, Elise,Boisvert, Luc,Liu, Ziping,Milburn, Claire,Tremblay, Maxime,Wei, Zhongyong,Woo, Simon,Luo, Xuehong,Cheng, Yun-Xing,Yang, Hua,Srivastava, Sanjay,Zhou, Fei,Brown, William,Tomaszewski, Miroslaw,Walpole, Christopher,Hodzic, Leila,St-Onge, Stéphane,Godbout, Claude,Salois, Dominic,Payza, Keymal

scheme or table, p. 3695 - 3700 (2009/04/04)

The preparation and evaluation of a novel class of CB2 agonists based on a benzimidazole moiety are reported. They showed binding affinities up to 1 nM towards the CB2 receptor with partial to full agonist potencies. They also demonstrated good to excellent selectivity (>1000-fold) over the CB1 receptor.

BENZIMIDAZOLES AND IMIDAZOPYRIDINES USEFUL IN THE TREATMENT OF DISEASES OR DISORDERS ASSOCIATED WITH CANNABINOID RECEPTOR 2 (CB2) SUCH AS PAIN

-

Page/Page column 50; 77, (2008/06/13)

This invention relates to novel benzimidazoles and imidazopyridines having the structural of formula I below and their pharmaceutically acceptable salts, tautomers or in vivo -hydrolysable precursors, compositions and methods of use thereof. These novel compounds provide treatments of CB2 associated disorders.

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