475489-15-7

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Basic information

Product Name: NVP-ADW742
Synonyms: NVP-ADW742;[5-(3-Benzyloxyphenyl)-7-[cis-3-[(pyrrolidin-1-yl)methyl]cyclobutyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amine;GSK 621659A;GSK 621659A [5-(3-Benzyloxyphenyl)-7-[cis-3-[(pyrrolidin-1-yl)methyl]cyclobutyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amine;5-[3-(PHENYLMETHOXY)PHENYL]-7-[CIS-3-(1-PYRROLIDINYLMETHYL)CYCLOBUTYL]-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE
CAS NO:475489-15-7
Molecular Formula: C28H31N5O
Molecular Weight: 453.57864
EINECS: -0
Product Categories: Inhibitors
Mol File: 475489-15-7.mol

Chemical Properties

Melting Point: N/A
Boiling Point: 677.5±55.0 °C(Predicted)
Flash Point: N/A
Appearance: /
Density: 1.31
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
PKA: 10.00±0.20(Predicted)
CAS DataBase Reference: NVP-ADW742(CAS DataBase Reference)
NIST Chemistry Reference: NVP-ADW742(475489-15-7)
EPA Substance Registry System: NVP-ADW742(475489-15-7)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 475489-15-7(Hazardous Substances Data)

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475489-15-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 475489-15-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,5,4,8 and 9 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 475489-15:
(8*4)+(7*7)+(6*5)+(5*4)+(4*8)+(3*9)+(2*1)+(1*5)=197
197 % 10 = 7
So 475489-15-7 is a valid CAS Registry Number.

475489-15-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name	5-[3-(Benzyloxy)phenyl]-7-[trans-3-(1-pyrrolidinylmethyl)cyclobut yl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine

1.2 Other means of identification

Product number	-
Other names	-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

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CANCER TREATMENT METHOD

-

Page/Page column 47, (2008/06/13)

The present invention relates to a method of treating cancer in a mammal and to pharmaceutical combinations useful in such treatment. In particular, the method relates to a cancer treatment method that includes administering an erb family inhibitor and an IGF-1R inhibitor to a mammal suffering from a cancer.

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