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6-(Benzyloxy)-4-chloro-7-methoxyquinoline-3-carboxamide is a complex organic compound belonging to the class of quinoline derivatives. It features a molecular formula of C21H16ClN3O3 and is characterized by the presence of a benzene ring, a chloro group, a methoxy group, and an amide group. 6-(Benzyloxy)-4-chloro-7-methoxyquinoline-3-carboxamide holds promise in medicinal chemistry and drug development due to its diverse biological activities, such as antifungal, antibacterial, and anticancer properties. Its unique structure offers a foundation for the research and development of innovative pharmaceutical agents with enhanced efficacy and potential therapeutic applications.

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  • 476193-59-6 Structure
  • Basic information

    1. Product Name: 6-(Benzyloxy)-4-chloro-7-methoxyquinoline-3-carboxamide
    2. Synonyms: 6-(Benzyloxy)-4-chloro-7-methoxyquinoline-3-carboxamide
    3. CAS NO:476193-59-6
    4. Molecular Formula: C18H15ClN2O3
    5. Molecular Weight: 342.7763
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 476193-59-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 529.4±50.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.338±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 14.65±0.30(Predicted)
    10. CAS DataBase Reference: 6-(Benzyloxy)-4-chloro-7-methoxyquinoline-3-carboxamide(CAS DataBase Reference)
    11. NIST Chemistry Reference: 6-(Benzyloxy)-4-chloro-7-methoxyquinoline-3-carboxamide(476193-59-6)
    12. EPA Substance Registry System: 6-(Benzyloxy)-4-chloro-7-methoxyquinoline-3-carboxamide(476193-59-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 476193-59-6(Hazardous Substances Data)

476193-59-6 Usage

Uses

Used in Pharmaceutical Industry:
6-(Benzyloxy)-4-chloro-7-methoxyquinoline-3-carboxamide is used as a precursor in the synthesis of novel pharmaceutical agents for various therapeutic applications. Its diverse biological activities, including antifungal, antibacterial, and anticancer properties, make it a valuable compound for the development of new drugs with improved efficacy.
Used in Antifungal Applications:
6-(Benzyloxy)-4-chloro-7-methoxyquinoline-3-carboxamide is used as an antifungal agent to combat fungal infections. Its structure allows for the inhibition of fungal growth and the disruption of essential fungal processes, making it a potential candidate for the treatment of various fungal diseases.
Used in Antibacterial Applications:
6-(Benzyloxy)-4-chloro-7-methoxyquinoline-3-carboxamide is employed as an antibacterial agent to target and eliminate bacterial infections. Its unique chemical structure enables it to interfere with bacterial cell functions, thereby inhibiting their growth and contributing to the development of new antibiotics.
Used in Anticancer Applications:
6-(Benzyloxy)-4-chloro-7-methoxyquinoline-3-carboxamide is utilized as an anticancer agent for the treatment of various types of cancer. Its ability to target and disrupt cancer cells, as well as its potential to synergize with existing chemotherapeutic drugs, makes it a promising compound for cancer therapy and the development of novel anticancer drugs.
Used in Drug Delivery Systems:
6-(Benzyloxy)-4-chloro-7-methoxyquinoline-3-carboxamide is used in the development of drug delivery systems to enhance the bioavailability, targeting, and therapeutic outcomes of pharmaceutical agents. Its chemical properties allow for the design of innovative drug carriers, such as nanoparticles and other delivery vehicles, to improve the efficacy and safety of drug administration.

Check Digit Verification of cas no

The CAS Registry Mumber 476193-59-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,6,1,9 and 3 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 476193-59:
(8*4)+(7*7)+(6*6)+(5*1)+(4*9)+(3*3)+(2*5)+(1*9)=186
186 % 10 = 6
So 476193-59-6 is a valid CAS Registry Number.

476193-59-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-chloro-7-methoxy-6-phenylmethoxyquinoline-3-carboxamide

1.2 Other means of identification

Product number -
Other names 6-(Benzyloxy)-4-chloro-7-methoxyquinoline-3-carboxamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:476193-59-6 SDS

476193-59-6Upstream product

476193-59-6Downstream Products

476193-59-6Relevant articles and documents

Identification of 3-amido-4-anilinoquinolines as potent and selective inhibitors of CSF-1R kinase

Scott, David A.,Balliet, Carrie L.,Cook, Donald J.,Davies, Audrey M.,Gero, Thomas W.,Omer, Charles A.,Poondru, Srinivasu,Theoclitou, Maria-Elena,Tyurin, Boris,Zinda, Michael J.

scheme or table, p. 697 - 700 (2009/08/15)

3-Amido-4-anilinoquinolines are potent and highly selective inhibitors of CSF-1R. Their synthesis and SAR is reported, along with initial efforts to optimize the physical properties and PK through modifications at the quinoline 6- and 7-positions.

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