476338-85-9 Usage
Uses
Used in Pharmaceutical Industry:
N-[4-(2-Amino-4-thiazolyl)phenyl]methanesulfonamide is used as an antiviral drug for the treatment of herpes zoster infection caused by the herpes zoster virus. It is effective in reducing the severity and duration of the infection by inhibiting the replication of the virus.
Used in Clinical Trials:
Amenamevir has been extensively studied in clinical trials, where it has shown promising results in the treatment of herpes zoster. Its antiviral activity and potential as an effective treatment for shingles and other herpes zoster virus infections have been validated through these trials.
Used in Antiviral Research:
The unique chemical structure of N-[4-(2-Amino-4-thiazolyl)phenyl]methanesulfonamide, including its thiazole ring and amine group, makes it a valuable compound for antiviral research. Further studies on its mechanism of action and potential applications in treating other viral infections can contribute to the development of new antiviral therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 476338-85-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,6,3,3 and 8 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 476338-85:
(8*4)+(7*7)+(6*6)+(5*3)+(4*3)+(3*8)+(2*8)+(1*5)=189
189 % 10 = 9
So 476338-85-9 is a valid CAS Registry Number.
476338-85-9Relevant articles and documents
HETEROCYCLIC COMPOUNDS AS CLASS II PHOSPHOINOSITIDE 3-KINASE INHIBITORS
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Page/Page column 83; 86, (2019/12/28)
The present application relates to compounds of formula (1) and their use as medicament, in particular for the treatment of a medical condition associated with defective PI3K signalling.
Design, synthesis and biological screening of new 4-thiazolidinone derivatives with promising COX-2 selectivity, anti-inflammatory activity and gastric safety profile
Abdellatif, Khaled R.A.,Abdelgawad, Mohamed A.,Elshemy, Heba A.H.,Alsayed, Shahinda S.R.
, p. 1 - 12 (2015/11/18)
Two series of new thiazolidin-4-one derivatives 4a-c and 8a-e were designed and prepared. All the synthesized compounds were evaluated for their in vitro COX-2 selectivity and anti-inflammatory activity in vivo. Compounds 8c and 8d showed the best overall
UREA DERIVATIVES METHODS FOR THEIR MANUFACTURE AND USES THEREOF
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Page/Page column 58, (2010/11/24)
The present invention provides compounds of formula (I): in which R 1, R'1, R2, R'2, R3, Y and G have the meanings given in the description, to a process for their preparation, their application by way of medicaments, and to pharmaceutical compositions containing them.
