- Synthesis and antifungal activity of benzo[d]oxazole-4,7-diones
-
Benzo[d]oxazole-4,7-diones were synthesized and tested for in vitro antifungal activity against fungi. Among them tested, many compounds showed good antifungal activity. The results suggest that benzo[d]oxazole-4,7-diones would be potent antifungal agents.
- Ryu, Chung-Kyu,Lee, Ra-Young,Kim, Na Young,Kim, Yang Hui,Song, Ae Li
-
-
Read Online
- CONDENSED HETEROCYCLIC COMPOUND
-
A compound represented by the general formula (I) [R1 represents a C1-6 alkyl group, a halogen atom, or the like; A represents a phenylene group, or the like; X represents —CH(R3)—, —O—, —NH—, or the like; Y represents —O—, —NH—, —N═, or —S—; . . . represents a single bond or double bond; n represents 1 to 3; R2 represents a C1-6 alkyl group, a C1-6 alkoxy group, or the like; and R3 represents hydrogen atom, a C1-6 alkyl group, or the like], or a salt thereof which has a blood LDL cholesterol-reducing action, and is useful as an active ingredient of medicaments.
- -
-
Paragraph 0270-0272
(2017/11/08)
-
- Diastereo- and enantioselective Pd(II)-catalyzed additions of 2-alkylazaarenes to N -boc imines and nitroalkenes
-
A chiral Pd(II)-bis(oxazoline) complex was found to be highly effective in promoting the first direct diastereo- and enantioselective addition of alkylazaarenes to N-Boc aldimines and nitroalkenes under mild conditions. Deprotection of Boc-protected products proceeded readily to provide amines in high yields.
- Best, Daniel,Kujawa, Szymon,Lam, Hon Wai
-
supporting information
p. 18193 - 18196
(2013/01/15)
-
- Synthesis and biological evaluation of novel heterocyclic quinones as inhibitors of the dual specificity protein phosphatase CDC25C
-
A focused set of heterocyclic quinones based on the benzothiazole, benzoxazole, benzimidazole, indazole and isoindole was prepared and screened with respect to the inhibition of the phosphatase activity of CDC25C. Benzoxazole- and benzothiazole-diones wer
- Lavergne, Olivier,Fernandes, Anne-Cecile,Brehu, Laetitia,Sidhu, Alban,Brezak, Marie-Christine,Prevost, Gregoire,Ducommun, Bernard,Contour-Galcera, Marie-Odile
-
p. 171 - 175
(2007/10/03)
-
- Benzothiazole-and benzoxazole-4, 7-dione derivatives and their use as dcd25 phosphatase inhibitors
-
The invention concerns the use as cdc25 phosphatase inhibitors, in particular cdc25-C phosphatase, and CD45 phosphatase, of compounds of general formula (I), wherein: W represents O or S. In accordance with the invention, the compounds of general formula
- -
-
Page/Page column 24
(2008/06/13)
-
- Product comprising at least one phosphatase cdc25 inhibitor combined with at least one other anticancer agent
-
A subject of the invention is a product comprising at least one Cdc25 phosphatase inhibitor in combination with at least one other anti-cancer agent for a therapeutic use which is simultaneous, separate or spread over time in the treatment of cancer. Acco
- -
-
Page/Page column 24
(2008/06/13)
-