Preparation of enantiopure sultams by intramolecular Diels-Alder reaction of furan-containing vinylsulfonamides
Enantiomerically pure δ- and γ-sultams have been prepared by intramolecular [4+2] cycloaddition of N-1-phenylethyl substituted vinylsulfonamides with purely thermal activation and under high pressure. An optimized procedure for reductive debenzylation of
Rogatchov, Viktor O.,Bernsmann, Heiko,Schwab, Pia,Fr?hlich, Roland,Wibbeling, Birgit,Metz, Peter