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BOC-D-PHE(3-I)-OH, also known as N-tert-butoxycarbonyl-3-iodo-D-phenylalanine, is a chemical compound that serves as a crucial building block in peptide synthesis. It features a phenylalanine molecule with a tert-butoxycarbonyl (BOC) protecting group and an iodine atom attached to the third carbon of the phenyl ring. BOC-D-PHE(3-I)-OH is recognized for its stability and compatibility with a range of chemical reactions, which makes it an indispensable tool in the creation of biologically active peptides and potential drug candidates for research and pharmaceutical applications.

478183-66-3

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478183-66-3 Usage

Uses

Used in Pharmaceutical Industry:
BOC-D-PHE(3-I)-OH is used as a key component in the synthesis of peptides and peptidomimetics for various pharmaceutical applications. Its role is pivotal in the development of new drugs and therapeutic agents due to its ability to be incorporated into peptide structures that can target specific biological pathways or receptors.
Used in Research Applications:
In research settings, BOC-D-PHE(3-I)-OH is utilized as a starting material for the preparation of complex peptide sequences. It aids scientists in exploring the structure-function relationships of peptides and in the discovery of novel bioactive molecules with potential applications in medicine.
Used in Peptide Synthesis:
BOC-D-PHE(3-I)-OH is used as a protected amino acid in peptide synthesis, where the BOC group serves to protect the amino group from unwanted side reactions during the synthesis process. This protection allows for the stepwise assembly of peptide chains with greater efficiency and yield.
Used in the Development of Biologically Active Peptides:
Due to its unique structure, BOC-D-PHE(3-I)-OH is used in the creation of biologically active peptides that can mimic or modulate the activity of natural peptides. These synthetic peptides can be designed to have enhanced stability, selectivity, and potency, making them valuable in therapeutic and diagnostic applications.
Used in Drug Candidate Development:
BOC-D-PHE(3-I)-OH contributes to the development of drug candidates by providing a versatile building block for the synthesis of novel peptide-based drugs. Its presence in a peptide sequence can influence the pharmacokinetic and pharmacodynamic properties of the drug, potentially leading to improved therapeutic efficacy and safety profiles.

Check Digit Verification of cas no

The CAS Registry Mumber 478183-66-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,8,1,8 and 3 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 478183-66:
(8*4)+(7*7)+(6*8)+(5*1)+(4*8)+(3*3)+(2*6)+(1*6)=193
193 % 10 = 3
So 478183-66-3 is a valid CAS Registry Number.

478183-66-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (2R)-3-(3-iodophenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid

1.2 Other means of identification

Product number -
Other names Boc-D-Phe(3-I)-OH

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:478183-66-3 SDS

478183-66-3Relevant articles and documents

Antibacterial macrocycles with substituted biphenyl

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Page/Page column 20, (2010/11/26)

The invention relates to antibacterial macrocycles with substituted biphenyl and processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially of bacterial infections.

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