478259-93-7

Basic information

• Product Name: 1-(4-FLUOROBENZYL)-4-(2-FURYL)-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBONITRILE
• Synonyms: 1-(4-FLUOROBENZYL)-4-(2-FURYL)-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBONITRILE
• CAS NO: 478259-93-7
• Molecular Formula: C17H11FN2O2
• Molecular Weight: 294.28
• Mol File: 478259-93-7.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(4-FLUOROBENZYL)-4-(2-FURYL)-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-FLUOROBENZYL)-4-(2-FURYL)-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBONITRILE(478259-93-7)
• EPA Substance Registry System: 1-(4-FLUOROBENZYL)-4-(2-FURYL)-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBONITRILE(478259-93-7)

Safety Data

• Hazardous Substances Data: 478259-93-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-(4-FLUOROBENZYL)-4-(2-FURYL)-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBONITRILE is used as a potential pharmaceutical agent for its suggested biological and pharmacological activities. Its complex molecular structure and the presence of the carbonitrile group make it a promising candidate for the development of new drugs and therapies.
Used in Organic Synthesis:
In the field of organic chemistry, 1-(4-FLUOROBENZYL)-4-(2-FURYL)-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBONITRILE is used as a reactive intermediate for the synthesis of various organic compounds. Its unique molecular structure allows for a wide range of reactions and the formation of diverse products.
Used in Medicinal Chemistry:
1-(4-FLUOROBENZYL)-4-(2-FURYL)-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBONITRILE is utilized as a key building block in the design and synthesis of novel bioactive molecules. Its heterocyclic nature and the presence of the carbonitrile group make it an attractive starting material for the development of new pharmaceuticals and therapeutic agents.
Used in Chemical Research:
1-(4-FLUOROBENZYL)-4-(2-FURYL)-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBONITRILE is also used in chemical research as a model system to study the properties and reactivity of complex molecular structures. Its diverse chemical makeup provides valuable insights into the behavior of similar compounds and contributes to the advancement of scientific knowledge in the field of chemistry.

Relevant articles and documents

1,4-DISUBSTITUTED 3-CYANO-PYRIDONE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2-RECEPTORS

The present invention relates to novel compounds, in particular novel pyridinone de- rivat ives according to Formula (I) wherein all radicals are defined in the application and claims. The compounds accord- ing to the invention are positive allosteric mod

NOVEL PYRIDINONE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2-RECEPTORS

The present invention relates to novel compounds, in particular novel pyridinone derivat ives according to Formula (I) X R1 N Y (I) R2 R3 wherein all radicals are defined in the application. The compounds according to the invention are positive allosteric modulators of metabotropic receptors-subt ype 2 ("mGluR2") which are useful for the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which the mGluR2 subtype of metabotropic receptors is involved. In particular, such diseases are central nervous system disorders selected from the group of anxiety, schizophrenia, migraine, depression, and epilepsy. The invention is also directed to pharmaceutical compositions and processes to prepare such compounds and compositions, as well as to the use of such compounds for the prevention and treatment of such diseases in which mGluR2 is involved. "