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Quinoline-8-tributylstannane is a chemical compound that combines the organic molecule quinoline, a heterocyclic aromatic compound with a nitrogen-containing ring, with tributylstannane, a tin derivative featuring three butyl groups. QUINOLINE-8-TRIBUTYLSTANNANE is recognized for its utility in organic synthesis, especially in the creation of carbon-carbon and carbon-heteroatom bonds, and is instrumental in facilitating reactions such as the Stille coupling, a prevalent cross-coupling technique in organic chemistry. Its distinctive structure and reactivity render it an invaluable asset for chemists in the synthesis of novel compounds and pharmaceuticals.

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  • 478282-21-2 Structure
  • Basic information

    1. Product Name: QUINOLINE-8-TRIBUTYLSTANNANE
    2. Synonyms: QUINOLINE-8-TRIBUTYLSTANNANE;8-(Tri-n-butylstannyl)quinoline;8-[Tris(but-1-yl)stannyl]quinoline;tributyl(quinolin-8-yl)stannane
    3. CAS NO:478282-21-2
    4. Molecular Formula: C21H33NSn
    5. Molecular Weight: 418.209
    6. EINECS: N/A
    7. Product Categories: Stannanes
    8. Mol File: 478282-21-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 447.2°C at 760 mmHg
    3. Flash Point: 224.2°C
    4. Appearance: /
    5. Density: N/A
    6. Vapor Pressure: 9.06E-08mmHg at 25°C
    7. Refractive Index: N/A
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: QUINOLINE-8-TRIBUTYLSTANNANE(CAS DataBase Reference)
    11. NIST Chemistry Reference: QUINOLINE-8-TRIBUTYLSTANNANE(478282-21-2)
    12. EPA Substance Registry System: QUINOLINE-8-TRIBUTYLSTANNANE(478282-21-2)
  • Safety Data

    1. Hazard Codes: T
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: 6.1
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 478282-21-2(Hazardous Substances Data)

478282-21-2 Usage

Uses

Used in Organic Synthesis:
Quinoline-8-tributylstannane is used as a reagent for facilitating the formation of carbon-carbon and carbon-heteroatom bonds, which are crucial in the synthesis of complex organic molecules. Its role in these reactions is to act as a precursor or catalyst, enhancing the efficiency and selectivity of bond formation processes.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, Quinoline-8-tributylstannane is utilized as a key intermediate in the synthesis of various medicinal compounds. Its unique properties allow for the development of new drugs with improved therapeutic profiles, contributing to advancements in drug discovery and medicinal chemistry.
Used in Cross-Coupling Reactions:
Specifically, Quinoline-8-tributylstannane is employed in Stille coupling reactions, a type of cross-coupling process widely used in organic chemistry. It serves as a coupling partner to form new carbon-carbon bonds, which are essential for constructing the backbones of many organic and pharmaceutical compounds. This application is particularly important for the synthesis of complex organic molecules that are difficult to access through traditional methods.

Check Digit Verification of cas no

The CAS Registry Mumber 478282-21-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,8,2,8 and 2 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 478282-21:
(8*4)+(7*7)+(6*8)+(5*2)+(4*8)+(3*2)+(2*2)+(1*1)=182
182 % 10 = 2
So 478282-21-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H6N.3C4H9.Sn/c1-2-6-9-8(4-1)5-3-7-10-9;3*1-3-4-2;/h1-5,7H;3*1,3-4H2,2H3;/rC21H33NSn/c1-4-7-16-23(17-8-5-2,18-9-6-3)20-14-10-12-19-13-11-15-22-21(19)20/h10-15H,4-9,16-18H2,1-3H3

478282-21-2 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Alfa Aesar

  • (H51471)  8-(Tri-n-butylstannyl)quinoline, 95%   

  • 478282-21-2

  • 250mg

  • 613.0CNY

  • Detail
  • Alfa Aesar

  • (H51471)  8-(Tri-n-butylstannyl)quinoline, 95%   

  • 478282-21-2

  • 1g

  • 1960.0CNY

  • Detail

478282-21-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name tributyl(quinolin-8-yl)stannane

1.2 Other means of identification

Product number -
Other names 8-[Tris(but-1-yl)stannyl]quinoline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:478282-21-2 SDS

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