478395-52-7 Usage
Uses
Used in Pharmaceutical Research:
1-Phenyl-5-(thiophen-2-yl)-1H-pyrazole is utilized as a key intermediate in the synthesis of novel drug candidates due to its unique chemical structure and potential biological activities. Its presence in various drug molecules contributes to their therapeutic effects, making it an indispensable component in the development of new pharmaceuticals.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-Phenyl-5-(thiophen-2-yl)-1H-pyrazole is employed as a structural motif to explore and optimize the properties of drug molecules. Its incorporation into various chemical scaffolds allows researchers to investigate its influence on the pharmacokinetics, pharmacodynamics, and overall efficacy of drug candidates, thereby enhancing their therapeutic potential.
Used in Synthetic Organic Chemistry:
1-Phenyl-5-(thiophen-2-yl)-1H-pyrazole serves as a versatile building block in synthetic organic chemistry, enabling the construction of complex molecular architectures. Its reactivity and compatibility with various synthetic strategies facilitate the development of new organic compounds with diverse applications, including pharmaceuticals, agrochemicals, and materials science.
Used in Drug Discovery:
1-Phenyl-5-(thiophen-2-yl)-1H-pyrazole is applied as a starting material in drug discovery processes, where its unique structural features and potential biological activities are leveraged to identify and optimize lead compounds. Its presence in various chemical libraries aids in high-throughput screening efforts, accelerating the discovery of new therapeutic agents with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 478395-52-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,8,3,9 and 5 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 478395-52:
(8*4)+(7*7)+(6*8)+(5*3)+(4*9)+(3*5)+(2*5)+(1*2)=207
207 % 10 = 7
So 478395-52-7 is a valid CAS Registry Number.
478395-52-7Relevant articles and documents
The application of vinylogous iminium salt derivatives to the regiocontrolled preparation of heterocyclic appended pyrazoles
Gupton, John T,Clough, Stuart C,Miller, Robert B,Norwood, Bradley K,Hickenboth, Charles R,Chertudi, Itta Bluhn,Cutro, Scott R,Petrich, Scott A,Hicks, Fred A,Wilkinson, Douglas R,Sikorski, James A
, p. 5467 - 5474 (2002)
A variety of vinylogous iminium salt derivatives have been examined as useful precursors for the regiocontrolled synthesis of heterocyclic appended pyrazoles. The reaction conditions for such processes have been optimized and the regiochemical preferences have been determined. Such reaction sequences represent methodologies which may have useful applications for the preparation of biologically interesting substances.
