479077-09-3 Usage
Uses
Used in Pharmaceutical Applications:
3-(2-Methoxyphenyl)-5-methyl-6-phenylisoxazolo-[4,5-c]pyridin-4(5H)-one is utilized as a target for drug development and research, aimed at treating various diseases and conditions. Its distinctive molecular structure and functional groups make it a promising candidate for the creation of new therapeutic agents.
Used in Chemical Synthesis:
In the field of chemical synthesis, 3-(2-Methoxyphenyl)-5-methyl-6-phenylisoxazolo-[4,5-c]pyridin-4(5H)-one serves as a building block for the creation of new compounds. Its properties and reactivity contribute to the development of novel chemical entities with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 479077-09-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,9,0,7 and 7 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 479077-09:
(8*4)+(7*7)+(6*9)+(5*0)+(4*7)+(3*7)+(2*0)+(1*9)=193
193 % 10 = 3
So 479077-09-3 is a valid CAS Registry Number.
479077-09-3Relevant articles and documents
Isoxazolopyridone derivatives as allosteric metabotropic glutamate receptor 7 antagonists
Nakamura, Masayuki,Kurihara, Hideki,Suzuki, Gentaroh,Mitsuya, Morihiro,Ohkubo, Mitsuru,Ohta, Hisashi
scheme or table, p. 726 - 729 (2010/05/18)
This Letter describes the synthesis and evaluation of mGluR7 antagonists in the isoxazolopyridone series. In the course of modification in this class, novel solid support synthesis of the isoxazolopyridone scaffold was developed. Subsequent chemical modification led to the identification of several potent derivatives with improved physicochemical properties compared to a hit compound 1. Among these, 2 showed good oral bioavailability and brain penetrability, suggesting that 2 may be useful for in vivo study to elucidate the role of mGluR7.
NOVEL ISOXAZOLOPYRIDONE DERIVATIVES AND USE THEREOF
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Page 16, (2010/11/30)
The invention relates to isoxazolopyridone derivatives of a formula (I-a): wherein R1a represents an optionally-substituted heteroaryl or phenyl group, R2a represents an optionally-substituted phenyl or heteroaryl group, and R3a
