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479543-46-9

VX-702 is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 6-(N-carbamoyl-2,6-difluoroanilino)-2-(2,4-difluorophenyl)pyridine-3-carboxamide

    Cas No: 479543-46-9

  • USD $ 1.9-2.9 / Gram

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  • 479543-46-9 Structure

  • Basic information

    1. Product Name: VX-702
    2. Synonyms: 1-(5-CarbaMoyl-6-(2,4-difluorophenyl)pyridin-2-yl)-1-(2,6-difluorophenyl)urea
    3. CAS NO:479543-46-9
    4. Molecular Formula: C19H12F4N4O2
    5. Molecular Weight: 404.322
    6. EINECS: N/A
    7. Product Categories: MAPK
    8. Mol File: 479543-46-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 555.2 °C at 760 mmHg
    3. Flash Point: 289.6 °C
    4. Appearance: /
    5. Density: 1.503 g/cm3
    6. Vapor Pressure: 2.28E-12mmHg at 25°C
    7. Refractive Index: 1.628
    8. Storage Temp.: Store at +4°C
    9. Solubility: N/A
    10. CAS DataBase Reference: VX-702(CAS DataBase Reference)
    11. NIST Chemistry Reference: VX-702(479543-46-9)
    12. EPA Substance Registry System: VX-702(479543-46-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 479543-46-9(Hazardous Substances Data)

479543-46-9 Usage

Uses

VX 702 is a p38 MAP kinase pathway inhibitor.

Biological Activity

Orally active, ATP-competitive inhibitor of p38α MAPK; also inhibits p38β (K D values are 3.7 and 17 nM respectively).

Check Digit Verification of cas no

The CAS Registry Mumber 479543-46-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,9,5,4 and 3 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 479543-46:
(8*4)+(7*7)+(6*9)+(5*5)+(4*4)+(3*3)+(2*4)+(1*6)=199
199 % 10 = 9
So 479543-46-9 is a valid CAS Registry Number.
InChI:InChI=1/C19H12F4N4O2/c20-9-4-5-10(14(23)8-9)16-11(18(24)28)6-7-15(26-16)27(19(25)29)17-12(21)2-1-3-13(17)22/h1-8H,(H2,24,28)(H2,25,29)

479543-46-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-(N-carbamoyl-2,6-difluoroanilino)-2-(2,4-difluorophenyl)pyridine-3-carboxamide

1.2 Other means of identification

Product number -
Other names Kinome_3176

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:479543-46-9 SDS

479543-46-9Downstream Products

479543-46-9Relevant articles and documents

SOLID FORMS OF 2-(2, 4-DIFLUOROPHENYL)-6-(1-(2,6-DIFLUOROPHENYL)UREIDO)NICOTINAMIDE

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Page/Page column 54-55, (2010/09/03)

This invention relates to solid forms of 2-(2, 4-difluorophenyl)-6-(l- (2,6-difluorophenyl)ureido)nicotinamide and pharmaceutical compositions thereof, and methods and uses therewith.

PROCESSES FOR PRODUCING PHENYL-6-(1-(PHENYL)UREIDO)NICOTINAMIDES)

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Page/Page column 26, (2010/09/03)

The present invention relates to processes for the preparation of compounds useful as inhibitors of p38 kinase. The processes of the present invention are amenable for large scale preparation and produce stable phenyl-6-(l-(phenyl)ureido)nicotinamides in

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