482584-84-9

Basic information

• Product Name: Carbamic acid, (5-formyl-4-methyl-2-thiazolyl)-, 1,1-dimethylethyl ester (9CI)
• Synonyms: Carbamic acid, (5-formyl-4-methyl-2-thiazolyl)-, 1,1-dimethylethyl ester (9CI)
• CAS NO: 482584-84-9
• Molecular Formula: C10H14N2O3S
• Molecular Weight: 242.29
• Mol File: 482584-84-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Carbamic acid, (5-formyl-4-methyl-2-thiazolyl)-, 1,1-dimethylethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (5-formyl-4-methyl-2-thiazolyl)-, 1,1-dimethylethyl ester (9CI)(482584-84-9)
• EPA Substance Registry System: Carbamic acid, (5-formyl-4-methyl-2-thiazolyl)-, 1,1-dimethylethyl ester (9CI)(482584-84-9)

Safety Data

• Hazardous Substances Data: 482584-84-9(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 7210-76-6 ethyl-2-amino-4-methylthiazole-5-carboxylate 
• 244236-52-0 ethyl 2-[[(tert-butyloxy)carbonyl]amino]-4-methyl-1,3-thiazole-5-carboxylate 
• 1215121-73-5 tert-butyl (5-(hydroxymethyl)-4-methylthiazol-2-yl)carbamate 

Relevant articles and documents

NOVEL COMPOUNDS

The present invention relates to novel compounds and methods for the manufacture of inhibitors of deubiquitylating enzymes (DUBs). In particular, the invention relates to the inhibition of ubiquitin C-terminal hydrolase L1 (UCHL1). The invention further relates to the use of DUB inhibitors in the treatment of cancer and other indications. Compounds of the invention include compounds having the formula (I) or a pharmaceutically acceptable salt thereof, wherein R1 to R8 are as defined herein.

TRICYCLIC SPIROCYCLE DERIVATIVES AND METHODS OF USE

The present invention relates to novel Tricyclic Spirocycle Derivatives, pharmaceutical compositions comprising the Tricyclic Spirocycle Derivatives and the use of these compounds for treating or preventing allergy, an allergy-induced airway response, congestion, a cardiovascular disease, an inflammatory disease, a gastrointestinal disorder, a neurological disorder, a metabolic disorder, obesity or an obesity-related disorder, diabetes, a diabetic complication, impaired glucose tolerance or aired fasting glucose.