cas 485832-96-0, 2-AMINO-6-FLUORO-3-NITROTOLUENE | Articles data ｜lookchem

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485832-96-0

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BENZIMIDAZOLE DERIVATIVES
The invention relates to benzimidazoles of Formula (I) and pharmaceutically acceptable salts thereof, wherein R1 to R6 are as defined in the description; to their use in medicine; to compositions containing them; to processes for their preparation; and to intermediates used in such processes. The benzimidazoles of Formula (I) are ITK inhibitors and are therefore potentially useful in the treatment of a wide range of disorders including, atopic dermatitis.
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Page/Page column 53; 122-123

(2021/06/26)

AZATRICYCLIC COMPOUNDS AND THEIR USE
Tricyclic nitrogen containing compounds),of formula (I) or a pharmaceutically, acceptable salt, solvate and/or N-oxide thereof: and their use as antibacterials.
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Page/Page column 49

(2008/06/13)

PYRROLO-QUINOXALINONE DERIVATIVES AS ANTIBACTERIALS
Tricyclic nitrogen containing compounds of the following Formula (I) and their use as antibacterials.
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(2008/06/13)

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Chemical Properties

Melting Point: 118-121
Boiling Point: 310.1 °C at 760 mmHg
Flash Point:141.4 °C
Density: 1.371 g/cm³
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
Vapor Pressure: 0.000611mmHg at 25°C
Refractive Index: 1.589
PKA: -1.55±0.25(Predicted)
PSA: 71.84000
LogP: 2.72890

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