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4-(6-fluoro-3-oxo-1,3-dihydro-2H-pyrazolo[4,3-c]quinolin-2-yl)benzoato(4-) is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 486449-65-4 Structure
  • Basic information

    1. Product Name: 4-(6-fluoro-3-oxo-1,3-dihydro-2H-pyrazolo[4,3-c]quinolin-2-yl)benzoato(4-)
    2. Synonyms: CD80-IN-3;4-(6-Fluoro-3-oxo-3,5-dihydro-2H-pyrazolo[4,3-c]quinolin-2-yl)benzoic acid;Benzoic acid, 4-(6-fluoro-3,5-dihydro-3-oxo-2H-pyrazolo[4,3-c]quinolin-2-yl)-
    3. CAS NO:486449-65-4
    4. Molecular Formula: C17H10FN3O3
    5. Molecular Weight: 323.278
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 486449-65-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 594.3°C at 760 mmHg
    3. Flash Point: 313.2°C
    4. Appearance: N/A
    5. Density: 1.536g/cm3
    6. Vapor Pressure: 5.67E-15mmHg at 25°C
    7. Refractive Index: 1.725
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. PKA: 4.18±0.10(Predicted)
    11. CAS DataBase Reference: 4-(6-fluoro-3-oxo-1,3-dihydro-2H-pyrazolo[4,3-c]quinolin-2-yl)benzoato(4-)(CAS DataBase Reference)
    12. NIST Chemistry Reference: 4-(6-fluoro-3-oxo-1,3-dihydro-2H-pyrazolo[4,3-c]quinolin-2-yl)benzoato(4-)(486449-65-4)
    13. EPA Substance Registry System: 4-(6-fluoro-3-oxo-1,3-dihydro-2H-pyrazolo[4,3-c]quinolin-2-yl)benzoato(4-)(486449-65-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 486449-65-4(Hazardous Substances Data)

486449-65-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 486449-65-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,8,6,4,4 and 9 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 486449-65:
(8*4)+(7*8)+(6*6)+(5*4)+(4*4)+(3*9)+(2*6)+(1*5)=204
204 % 10 = 4
So 486449-65-4 is a valid CAS Registry Number.

486449-65-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(6-fluoro-3-oxo-1H-pyrazolo[4,3-c]quinolin-2-yl)benzoic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:486449-65-4 SDS

486449-65-4Upstream product

486449-65-4Relevant articles and documents

Novel immunomodulating compounds

-

, (2008/06/13)

The present invention relates to a novel heterocyclic compound, a pharmaceutical composition comprisining said compound, a method and use of said compound for clinical treatment of medical conditions which may benefit from immunomodulation, e.g. rheumatoid arthritis, multiple sclerosis, diabetes, asthma, transplantation, systemic lupus erythematosis and psoriasis. More particularly the present invention relates to novel heterocyclic compounds, which are CD80 antagonists capable of inhibiting the interactions between CD80 and CD28. A method of screening compounds for their ability of inhibiting ligand-induced co-stimulatory receptor internalisation pathways in immune competent human cells is described. Said immune competent human cells are incubated at conditions capable of inducing co-stimulatory receptor internalisation in the presence of at least one test compound and the suppression of the ligand-induced co-stimulatory receptor internalisation determined. There is also described a kit for use in such a method, as well as an immunoregulatory drug capable of blocking down-modulation of a ligand-induced receptor.

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