493-95-8 Usage
Uses
Used in Antiviral Applications:
Savinin is used as an antiviral agent for its potent activity against severe acute respiratory syndrome Coronavirus (SARS-CoV). It targets the viral replication process, inhibiting the spread of the virus and reducing the severity of the infection.
Used in Anti-cancer Applications:
Savinin is used as an anti-cancer agent, particularly in the treatment of various types of cancer. It has been shown to induce apoptosis in cancer cells, inhibiting their growth and proliferation. Additionally, it may enhance the effectiveness of conventional chemotherapy by increasing chemo-sensitivity in resistant cases.
Used in Anti-inflammatory Applications:
Savinin is used as an anti-inflammatory agent, helping to reduce inflammation and alleviate pain associated with various conditions. Its ability to modulate inflammatory signaling pathways makes it a potential therapeutic option for treating inflammatory diseases.
Used in Drug Delivery Systems:
To improve the bioavailability and therapeutic outcomes of savinin, novel drug delivery systems have been developed. These systems, which may include organic and metallic nanoparticles, aim to enhance the delivery of savinin to target cells, increasing its efficacy and reducing potential side effects.
Used in Pharmaceutical Industry:
Savinin is used as a pharmaceutical compound for its diverse range of biological activities. Its potential applications in antiviral, anti-cancer, and anti-inflammatory treatments make it a valuable asset in the development of new drugs and therapies.
Used in Nutraceutical Industry:
Savinin is used as a nutraceutical ingredient for its health-promoting properties. It can be incorporated into dietary supplements and functional foods to support immune function, reduce inflammation, and promote overall health and well-being.
Check Digit Verification of cas no
The CAS Registry Mumber 493-95-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,9 and 3 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 493-95:
(5*4)+(4*9)+(3*3)+(2*9)+(1*5)=88
88 % 10 = 8
So 493-95-8 is a valid CAS Registry Number.
InChI:InChI=1/C20H16O6/c21-20-15(6-13-2-4-17-19(8-13)26-11-24-17)14(9-22-20)5-12-1-3-16-18(7-12)25-10-23-16/h1-4,6-8,14H,5,9-11H2/b15-6+/t14-/m0/s1
493-95-8Relevant articles and documents
Asymmetric synthesis of lignans using oxazolidinones as chiral auxiliaries
Charlton, James L.,Chee, Gaik-Lean
, p. 1076 - 1083 (2007/10/03)
A simple procedure for the asymmetric synthesis of lignans via chiral β-benzyl-γ-butyrolactones has been developed. The key benzylbutyrolactone intermediates were efficiently synthesized using a six-step procedure, starting from 3,4-(methylenedioxy)cinnamic acid. The key step in this sequence was a highly diastereoselective alkylation of an N-acyloxazolidinone enolate. The resulting β-benzyl-γ-butyrolactones were subsequently transformed into the benzylidene lignans gossypifan and savinin (hibalactone) via aldol condensation-dehydration reactions, and into the dibenzylbutyrolactone lignan 4′-demethylyalein, through alkylation. Oxidation of 4′-demethylyatein with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) afforded cis- and trans-benzylidenebenzylbutyrolactones, whereas oxidation with DDQ/TFA gave 4′-demethyl-deoxyisopodophyllotoxin.
Chiral Synthesis of Lignan Lactones, (-)-Hinokinin, (-)-Deoxypodorhizone, (-)-Isohibalactone and (-)-Savinin by Means of Enantioselective Deprotonation
Honda, Toshio,Kimura, Nobuaki,Sato, Shigeki,Kato, Daishiro,Tominaga, Hideo
, p. 1043 - 1046 (2007/10/02)
Chiral synthesis of lignan lactones, (-)-hinokinin, (-)-deoxypodorhizone, (-)-isohibalactone and (-)-savinin, has been achieved by employing an enantioselective deprotonation of 3-(3,4-methylenedioxybenzyl)cyclobutanone with lithium (S,S')-α,α'-dimethylbenzylamide, as a key step.
