496056-53-2

Basic information

• Product Name: 4-(3-METHYL-BENZYL)-PIPERIDINE
• Synonyms: 4-(3-METHYL-BENZYL)-PIPERIDINE
• CAS NO: 496056-53-2
• Molecular Formula: C₁₃H₁₉N
• Molecular Weight: 189.3
• Mol File: 496056-53-2.mol

Chemical Properties

• Boiling Point: 298.3°C at 760 mmHg
• Flash Point: 137.1°C
• Appearance: /
• Density: 0.96g/cm³
• Vapor Pressure: 0.00128mmHg at 25°C
• Refractive Index: 1.525
• CAS DataBase Reference: 4-(3-METHYL-BENZYL)-PIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-METHYL-BENZYL)-PIPERIDINE(496056-53-2)
• EPA Substance Registry System: 4-(3-METHYL-BENZYL)-PIPERIDINE(496056-53-2)

Safety Data

• Hazardous Substances Data: 496056-53-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H19N/c1-11-3-2-4-13(9-11)10-12-5-7-14-8-6-12/h2-4,9,12,14H,5-8,10H2,1H3

Upstream product

• 93189-15-2 α-(3-methylphenyl)-4-pyridinemethanol 
• 28987-79-3 m-tolylmagnesium bromide 
• 872-85-5 pyridine-4-carbaldehyde 

Relevant articles and documents

20-HETE FORMATION INHIBITORS

This disclosure provides novel heterocyclic compounds and methods for inhibiting the enzyme CYP4. Further disclosed methods include: a method of inhibiting the biosynthesis of 20-hydroxyeicosatetraenoic acid (20-HETE) in a subject in need thereof and a method of producing neuroprotection and decreased brain damage by preventing cerebral microvascular blood flow impairment and anti-oxidant mechanisms in a subject experiencing or having experienced an ischemic event.

NEW BENZOYL UREA DERIVATIVES

The new benzoyl urea derivatives of formula (I) wherein the meaning of X and Y independently are hydrogen atom, hydroxy, benzyloxy, amino, nitro, C1-C4 alkylsulfonamido optionally substituted with a halogen atom or halogen atoms, Cs

Convenient, benign and scalable synthesis of 2- and 4-substituted benzylpiperidines

A short, scalable and environmentally benign synthesis of 2- and 4-substituted benzylpiperidines has been developed. The method is based on the temperature-programmed consecutive deoxygenation and heteroaromatic ring saturation of aryl(pyridin-2-yl)- and aryl(pyridin-4-yl)methanols and aryl(pyridin-4-yl)methanones in the presence of Pd/C catalyst. The crucial roles of the temperature, the acidity and the substrate structure in the change of selectivity have been demonstrated by isolation of several substituted aryl(piperidine)methanols. The carbinols and ketones were prepared from commercially available pyridinecarbaldehydes or 4-cyanopyridine and substituted bromobenzenes via organometallic intermediates. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.

Hypolipidemic alkenesulfonamides

Method for lowering blood liped levels in mammals, using certain derivatives of N-carbamoyl-2-phenylethenesulfonamide, many of which are novel.