496863-32-2

Basic information

• Product Name: Benzenepropanamide, N-methyl--bta--methylene-N-[5-(methylthio)-2-furanyl]-
• Synonyms: Benzenepropanamide, N-methyl--bta--methylene-N-[5-(methylthio)-2-furanyl]-
• CAS NO: 496863-32-2
• Molecular Formula: C₁₆H₁₇NO₂S
• Molecular Weight: 287.37668
• Mol File: 496863-32-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzenepropanamide, N-methyl--bta--methylene-N-[5-(methylthio)-2-furanyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanamide, N-methyl--bta--methylene-N-[5-(methylthio)-2-furanyl]-(496863-32-2)
• EPA Substance Registry System: Benzenepropanamide, N-methyl--bta--methylene-N-[5-(methylthio)-2-furanyl]-(496863-32-2)

Safety Data

• Hazardous Substances Data: 496863-32-2(Hazardous Substances Data)

Upstream product

• 438044-55-4 2,2-dimethylpropanoic acid 1-[(methylcarbamoyl)methyl]-2,2-bis(methylsulfanyl)ethyl ester 
• 496863-31-1 2,2-dimethylpropanoic acid 1-[bis(methylsulfanyl)methyl]-3-[methyl(3-phenylbut-3-enoyl)amino]-3-oxopropyl ester 

Downstream Products

• 496863-35-5 1-methyl-6-(methylsulfanyl)-3a-phenyl-2,3,3a,4-tetrahydroindol-2-one 

Relevant articles and documents

A new construct of the cis-3a-aryloctahydroindole skeleton via the [4+2] cycloaddition of furanyl carbamates

Several 2-methylthio-5-amidofurans containing tethered unsaturation were prepared via the reaction of dimethyl(methylthio)-sulfonium tetrafluoroborate (DMTSF) with β-alkoxy-γ-dithiane amides. Thermolysis of these furans resulted in an intramolecular Diels-Alder reaction (IMDAF). The resulting oxa-bridged cycloadducts underwent a subsequent rearrangement to form bicyclic lactams. Model studies were directed toward mesembrine as well as the core skeleton of the 3,4-benzoerythrinane skeleton. Using this cascade sequence, a formal synthesis of the alkaloid erysotrine was accomplished.