497066-81-6

Basic information

• Product Name: 1H-1,4-Benzodiazepine-3,5(2H,4H)-dione,4-ethyl-(9CI)
• Synonyms: 1H-1,4-Benzodiazepine-3,5(2H,4H)-dione,4-ethyl-(9CI)
• CAS NO: 497066-81-6
• Molecular Formula: C11H12N2O2
• Molecular Weight: 204.22518
• Product Categories: ETHYL
• Mol File: 497066-81-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-1,4-Benzodiazepine-3,5(2H,4H)-dione,4-ethyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-1,4-Benzodiazepine-3,5(2H,4H)-dione,4-ethyl-(9CI)(497066-81-6)
• EPA Substance Registry System: 1H-1,4-Benzodiazepine-3,5(2H,4H)-dione,4-ethyl-(9CI)(497066-81-6)

Safety Data

• Hazardous Substances Data: 497066-81-6(Hazardous Substances Data)

Upstream product

• 32212-29-6 2-amino-N-ethylbenzamide 
• 771478-60-5 4-ethyl-1-nitroso-1H-1,4-benzodiazepine-3,5(2H,4H)-dione 

Relevant articles and documents

Synthesis of 1,4-benzodiazepine-3,5-diones

Even though benzodiazepines have a strong position in medicinal chemistry, very few synthetic routes to 1H-1,4-benzodiazepine-3,5(2H,4H)-diones have ever been published and the claimed products have often been poorly characterized. Through the present wor

Synthesis and pharmacological activity of 1,4-benzodiazepine derivatives

2-Aminobenzamides (3a-g) were prepared starting with isatoic anhydride. These compounds reacted with chloroacetic acid to give (4a-g), which were cyclized by dicyclohexylcorbodiimide to afford (5a-g). The preliminary pharmacological screening revealed tha