Novel estrogen receptor ligands based on an anthranylaldoxime structure: Role of the phenol-type pseudocycle in the binding process
The 3,4-diphenylsalicylaldoxime system 1 is an estrogen receptor (ER) ligand of unusual structure, having a hydrogen-bonded pseudocyclic A′-ring in place of the paradigmatic phenolic A-ring that is characteristic of most estrogens. We have investigated th
Minutolo, Filippo,Antonello, Michela,Bertini, Simone,Ortore, Gabriella,Placanica, Giorgio,Rapposelli, Simona,Sheng, Shubin,Carlson, Kathryn E.,Katzenellenbogen, Benita S.,Katzenellenbogen, John A.,Macchia, Marco
p. 4032 - 4042
(2007/10/03)
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