499771-03-8Relevant articles and documents
Azo dyes containing 1,3,4-thiadiazole fragment: Synthesis and properties
Amosov, Evgeny,Bagryanskaya, Irina,Karpova, Elena,Selivanova, Galina,Shundrina, Inna,Skolyapova, Alexandrina,Wang, Jiaying
, p. 1929 - 1942 (2022/01/31)
New 1,3,4-thiadiazole derivatives containing a diazenyl group, as well as both a diazenyl and an imino group, were synthesized and their optical and thermal properties were investigated. Initially, new azo compounds containing an azo group directly in the thiadiazole block were obtained by the coupling of diazonium bisulfates based on the previously known 5-derivatives of 2-amino-1,3,4-thiadiazoles with N,N-dialkyl anilines (N(n-Bu)2, NEt2, and NEt(EtOH)). Schiff bases were obtained by the interaction of p-toluidine, p-phenylenediamine and p-aminophenol with azo compounds containing an aldehyde group in the 1,3,4-thiadiazole ring. The new dyes were characterized by spectral (IR, UV, 1H NMR, 13C NMR and mass spectra) and X-ray analyses. This journal is
CARBACEPHEM BETA-LACTAM ANTIBIOTICS
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Page/Page column 90, (2010/04/06)
Carbacephem β-lactam antibiotics having structure (I) are disclosed, including stereoisomers, pharmaceutically acceptable salts, esters and prodrugs thereof, wherein Ar2, X, R1 and R2 are as defined herein. The compounds are useful for the treatment of bacterial infections, in particular those caused by methicillin-resistant Staphylococcus spp.