TYROSINE AMIDE DERIVATIVES AS RHO- KINASE INHIBITORS
Bicyclic dihydropyrimidine-carboxamide compounds of formula I described herein inhibit Rho Kinase and may be used for the treatment of many disorders associated with ROCK enzymes mechanisms, such as pulmonary diseases including asthma, chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH).
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Paragraph 0443-0444; 0511-0512
(2018/08/20)
Synthesis and in vitro evaluation of 18F labeled tyrosine derivatives as potential positron emission tomography (PET) imaging agents
Three new 18F labeled fluoroalkyl tyrosine derivatives, O-(2-[18F]fluoroethyl)-α-methyltyrosine (FEMT, [ 18F]2), O-(2-[18F]fluoroethyl)-2-l-azatyrosine (FEAT, [18F]3), O-(2-[18F]fluoroethyl
Wang, Limin,Qu, Wenchao,Lieberman, Brian,Ploessl, Karl,Kung, Hank F.
scheme or table
p. 3482 - 3485
(2010/08/22)
Compositions and Methods for Cellular Imaging and Therapy
The present invention relates generally to the fields of chemistry and radionuclide imaging. More particularly, it concerns compositions, kits and methods for imaging and therapy involving N4 compounds and derivatives.
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Page/Page column 39
(2008/06/13)
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