501378-42-3

Basic information

• Product Name: 2-Pyridinecarbonitrile,6-(methylthio)-(9CI)
• Synonyms: 2-Pyridinecarbonitrile,6-(methylthio)-(9CI)
• CAS NO: 501378-42-3
• Molecular Formula: C7H6N2S
• Molecular Weight: 150.204
• Product Categories: PYRIDINE
• Mol File: 501378-42-3.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Pyridinecarbonitrile,6-(methylthio)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinecarbonitrile,6-(methylthio)-(9CI)(501378-42-3)
• EPA Substance Registry System: 2-Pyridinecarbonitrile,6-(methylthio)-(9CI)(501378-42-3)

Safety Data

• Hazardous Substances Data: 501378-42-3(Hazardous Substances Data)

Upstream product

• 87512-29-6 2-chloro-6-(methylsulfonyl)pyridine 
• 2402-78-0 2,6-dichloropyridine 
• 33252-29-8 6-chloro-pyridine-2-carbonitrile 
• 5188-07-8 sodium thiomethoxide 

Relevant articles and documents

Imide-catalyzed oxidation system: Sulfides to sulfoxides and sulfones

R1SR2 Imide(cat.), → Toulene or DME R 1SOR2 R1SO2R2 A new combination system, the oxidation of sulfides using aqueous NaOCl in the presence of a catalytic amount of imide under two-phase conditions, has been developed. The combination effectively converts various sulfides to the corresponding sulfoxides and sulfones. It was deduced that the imide could react with NaOCl to produce N-chloroimide, which would play roles of both the active oxidizing reagent and phase transfer catalyst.

1,3-BENZOTHIAZINONE DERIVATIVES AND USE THEREOF

This invention provides a compound represented by the formula (I) :wherein R1 is a hydrogen atom, a halogen atom, hydroxy, nitro, optionally halogenated alkyl, alkoxy optionally having substituents, acyl or amino optionally having substituents;R2 is pyridyl, furyl, thienyl, pyrrolyl, quinolyl, pyrazinyl, pyrimidinyl, pyridazinyl, indolyl, tetrahydroquinolyl or thiazolyl, each of which may have substituents;n is 1 or 2; or a salt. And this invention provides a safe pharmaceutical comprising the compound of the formula (I) , which has an excellent apoptosis inhibitory effect and MIF binding effect, for preventing and/or treating heart disease, nervous degenerative disease, cerebrovascular disease, central nervous infectious disease, traumatorathy, demyelinating disease, bone and articular disease, kidney disease, liver disease, osteomyelodysplasia, AIDS, cancer, and the like.