501927-29-3 Usage
Uses
Used in Pharmaceutical Research:
MN-25 is used as a research compound for investigating the role of CB2 receptors in various physiological and pathological processes. Its higher affinity for the CB2 receptor makes it a useful tool in exploring the potential therapeutic effects of targeting this receptor, particularly in conditions where CB2 activation may provide benefits.
Used in Forensic Analysis:
MN-25 is utilized as a forensic standard for the identification and quantification of synthetic cannabinoids in biological samples. Its unique binding profile and synthetic nature make it a valuable reference compound for forensic laboratories working to detect and analyze the presence of synthetic cannabinoids in cases related to drug abuse or intoxication.
Used in Drug Development:
MN-25 serves as a lead compound in the development of novel therapeutic agents targeting the CB2 receptor. Its selective activation of the CB2 receptor over the CB1 receptor may offer advantages in the treatment of certain conditions, such as inflammation, pain, and autoimmune disorders, without the psychoactive effects associated with CB1 receptor activation.
Used in Preclinical Studies:
MN-25 is employed as a test compound in preclinical studies to evaluate the safety, efficacy, and pharmacokinetics of CB2 receptor agonists. These studies help to determine the potential therapeutic applications of MN-25 and similar compounds, as well as their suitability for further development as drug candidates.
Check Digit Verification of cas no
The CAS Registry Mumber 501927-29-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,1,9,2 and 7 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 501927-29:
(8*5)+(7*0)+(6*1)+(5*9)+(4*2)+(3*7)+(2*2)+(1*9)=133
133 % 10 = 3
So 501927-29-3 is a valid CAS Registry Number.
501927-29-3Relevant articles and documents
C-3 Amido-indole cannabinoid receptor modulators
Hynes Jr., John,Leftheris, Katerina,Wu, Hong,Pandit, Chennagiri,Chen, Ping,Norris, Derek J.,Chen, Bang-Chi,Zhao, Rulin,Kiener, Peter A.,Chen, Xiaorong,Turk, Lori A.,Patil-Koota, Vina,Gillooly, Kathleen M.,Shuster, David J.,McIntyre, Kim W.
, p. 2399 - 2402 (2007/10/03)
C-3 Amido-indoles were found to selectively bind to the CB2 receptor. SAR studies led to optimized compounds with excellent in vivo potency against LPS induced TNF-α release in murine models of cytokine production.
