502132-86-7

Basic information

• Product Name: 3-Amino-5-(2-fluorophenyl)-1H-pyrazole
• Synonyms: 3-Amino-5-(2-fluorophenyl)-1H-pyrazole;5-(2-Fluorophenyl)-2H-pyrazol-3-aMine;5-(2-fluorophenyl)-1H-Pyrazol-3-amine
• CAS NO: 502132-86-7
• Molecular Formula: C₉H₈FN₃
• Molecular Weight: 177.18
• Mol File: 502132-86-7.mol

Chemical Properties

• Boiling Point: 427.6 °C at 760 mmHg
• Flash Point: 212.4 °C
• Appearance: /
• Density: 1.334 g/cm³
• Vapor Pressure: 1.62E-07mmHg at 25°C
• Refractive Index: 1.636
• CAS DataBase Reference: 3-Amino-5-(2-fluorophenyl)-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Amino-5-(2-fluorophenyl)-1H-pyrazole(502132-86-7)
• EPA Substance Registry System: 3-Amino-5-(2-fluorophenyl)-1H-pyrazole(502132-86-7)

Safety Data

• Hazard Codes: Xn
• Statements: 22-37/38-41
• Safety Statements: 26-36/39
• Hazardous Substances Data: 502132-86-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research and Drug Design:
3-Amino-5-(2-fluorophenyl)-1H-pyrazole is used as a building block for the synthesis of new drugs and bioactive molecules, owing to its unique chemical structure and reactivity. Its presence in the development of pharmaceutical compounds can contribute to the discovery of novel therapeutic agents with improved efficacy and selectivity.
Used in Medicinal Chemistry:
3-Amino-5-(2-fluorophenyl)-1H-pyrazole is utilized as a key component in the design and synthesis of pharmaceutical compounds, allowing researchers to explore its potential in treating various diseases and conditions. Its incorporation into drug candidates can lead to the development of innovative treatments with enhanced pharmacological properties.
Used in Organic Synthesis:
3-Amino-5-(2-fluorophenyl)-1H-pyrazole serves as a versatile intermediate in organic synthesis, enabling the creation of a wide range of organic compounds with diverse applications. Its unique structure and reactivity make it an attractive candidate for the synthesis of complex organic molecules, including those with potential applications in various industries.

InChI:InChI=1/C9H8FN3/c10-7-4-2-1-3-6(7)8-5-9(11)13-12-8/h1-5H,(H3,11,12,13)

Upstream product

• 31915-26-1 3-(2-fluorophenyl)-3-oxo-propanenitrile 

Relevant articles and documents

ANTAGONISTS OF THE ADENOSINE A2A RECEPTOR

The present invention relates to compounds of formula I shown below: wherein R0, R1, R2, R3 and A are each as defined in the application. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of diseases or conditions in which adenosine A2a receptor activity is implicated, such as, for example, cancer.

ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR INHIBITORS

The present invention provides compounds and compositions, methods of making them, and methods of using them to modulate α7 nicotinic acetylcholine receptors and/or to treat any of a variety of disorders, diseases, and conditions. Provided compounds can a

NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS

The present invention provides compounds of formula (I) and compositions thereof, methods of making them, and methods of using them to modulate alpha7 nicotinic acetylcholine receptors and/or to treat any of a variety of disorders, diseases, and conditions. Provided compounds can affect, among other things, neurological, psychiatric and/or inflammatory system.